NAKLOFEN INJECTION 75MG/3ML

Physicians prescribe the medicinal product for the treatment of diseases which require anti-inflammatory and / or analgesic effects

INGREDIENTS
The active substance is diclofenac sodium (diclofenac sodium). Each ml of solution for injection contains 25 mg of diclofenac sodium. Each 3 ml solution for injection ( 1 vial ) containing 75 mg of diclofenac sodium.
Other ingredients are benzyl alcohol, propylene glycol ( E1520 ), sodium metabisulphite ( E223 ), sodium hydroxide ( E542 ), water for injections.

INDICATION
• Step of inflammatory and degenerative forms of joint diseases, rheumatoid arthritis, juvenile chronic arthritis, ankylosing spondylitis, osteoarthritis and spondilatroza, pain syndromes of the spine, non-arthritic rheumatism
• gouty
• painful and inflammatory conditions in gynecology (primary dysmenorrhea)
• Renal and biliary colic
• Postgravmatichna and postoperative pain
• Severe migraine attacks

DOSAGE

Solution for injection ( 75 mg / 3 ml),
1 ampoule i.m. once or twice a day

SIDE EFFECTS

Common: affects 1 to 10 users in 100): nausea , diarrhea, constipation , abdominal pain, dyspepsia, flatulence, headache, dizziness, increased activity of liver enzymes, rash, injection site , pain , irritation and induration ;

Rare ( affects 1 to 10 users in 10,000 ) : bleeding , ulcers, perforation , jaundice, liver function abnormalities ( asymptomatic hepatitis, acute hepatitis, chronic active hepatitis), violation of the normal flow of bile from the liver to the intestine ( cholestasis ) , drowsiness , fatigue , kidney failure , blood in the urine ( hematuria ) , hives ( urticaria), hypersensitivity reactions (bronchospasm , angioedema , anaphylactic shock) , fluid retention (edema), respiratory (asthma, dyspnoea)

CONTRAINDICATION

• Known hypersensitivity (e.g., anaphylactic reactions and serious skin reactions) to diclofenac or any components of the drug product (see WARNINGS; Anaphylactic Reactions, Serious Skin Reactions).
• History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs. Severe, sometimes fatal, anaphylactic reactions to NSAIDs have been reported in such patients (see WARNINGS; Anaphylactic Reaction, Exacerbation Of Asthma Related To Aspirin Sensitivity).
• In the setting of coronary artery bypass graft (CABG) surgery (see WARNINGS; Cardiovascular Thrombotic Events).
• Active, gastric or intestinal ulcer, bleeding or perforation.
• Established congestive heart failure (NYHA II-IV), ischemic heart disease, peripheral arterial disease and/or cerebrovascular disease.
• Severe heart failure, hepatic failure and renal failure.
• History of gastro-intestinal bleeding or perforation, relating to previous NSAID therapy.
• During the last trimester of pregnancy

STORAGE NOTE

Keep out of reach of children
Do not use the medicine after the expiry date stated on the packaging. The expiry date refers to the last day of that month.
Do not store above 25 ° C.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.