NATAMYCIN EYE DROP 

Natamycin eye drop is indicated for the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms including Fusarium solani keratitis.

ACTIVE INGREDIENT 

Each mL of the suspension contains:

Active: natamycin 5% (50mg).

Preservative: benzalkonium chloride 0.02%.

Inactive: sodium hydroxide and/or hydrochloric acid (neutralized to adjust the pH), purified water.

DOSAGE 

The preferred initial dosage in fungal keratitis is one drop of NATACYN® (natamycin ophthalmic suspension) 5% instilled in the conjunctival sac at hourly or two-hourly intervals.

The frequency of application can usually be reduced to one drop 6 to 8 times daily after the first 3 to 4 days. Therapy should generally be continued for 14 to 21 days or until there is resolution of active fungal keratitis.

In many cases, it may be helpful to reduce the dosage gradually at 4 to 7day intervals to assure that the replicating organism has been eliminated. Less frequent initial dosage (4 to 6 daily applications) may be sufficient in fungal blepharitis and conjunctivitis.

SHAKE WELL BEFORE USING.

SIDE EFFECTS 

Allergic reaction, change in vision, chest pain, corneal opacity, dyspnea, eye discomfort, eye edema, eye hyperemia, eye irritation, eye pain, foreign body sensation, paresthesia, and tearing.

WARNINGS AND PRECAUTIONS 

FOR TOPICAL OPHTHALMIC USE ONLY — NOT FOR INJECTION.

Failure of improvement of keratitis following 7-10 days of administration of the drug suggests that the infection may be caused by a microorganism not susceptible to natamycin.

STORAGE

Store between 2-24ºC (36-75ºF).

Do not freeze.

Avoid exposure to light and excessive heat