Description:

Agycin Azithromycin suspension 15ml by BLISS (often listed under Bliss GVS Pharma or associated with “we care” branding in some African markets like Ghana) is a paediatric antibiotic in powder form for oral suspension. It is used to treat mild to moderate bacterial infections caused by susceptible organisms, including respiratory tract infections (e.g., pharyngitis/tonsillitis, sinusitis, pneumonia), skin/soft tissue infections, ear infections (otitis media), and other conditions like typhoid fever or certain STIs (e.g., chlamydia). Azithromycin inhibits bacterial protein synthesis, providing broad-spectrum coverage with convenient short-course dosing.

Prescription: Prescription-only (Rx). Requires a doctor’s prescription (typically for confirmed or suspected bacterial infection with culture/sensitivity where possible); regulated in Ghana and available through pharmacies (imported generic).

Therapeutic Category:

Antibacterial / Macrolide antibiotic (azalide subclass for community-acquired and atypical bacterial infections).

Active Ingredients/Composition:

Powder for oral suspension: Azithromycin (as dihydrate) USP equivalent to azithromycin anhydrous 40 mg per ml after reconstitution (400 mg/10 ml total in 15 ml bottle, yielding ~40 ml suspension when water added). Excipients: Kyron T-112 BN (suspending agent), sucrose, aspartame (sweetener), Powdarome Peppermint Premium (flavor), xanthan gum, and others (refer to label for full list).

Vitamins: None.

Minerals: None.

Variant: 40 mg/ml (400 mg/10 ml) powder for oral suspension in 15 ml HDPE bottle (reconstitutes to ~40 ml; paediatric-focused single-dose or short-course pack; differs from tablet forms or higher-volume suspensions).

Consume Type:

Oral (suspension; reconstituted liquid; shake well before each use; measured with spoon/syringe).

Directions/Usage: Reconstitution: Add water to the bottle (as marked), shake to disperse powder, then add more water to the mark for 40 ml final volume. Dosage (weight-based for children; standard azithromycin paediatric guidelines):

• Otitis media/sinusitis/pharyngitis: 10 mg/kg once daily for 3 days or 30 mg/kg single dose.
• Typical examples:
  • 15-25 kg: 5 ml once daily Days 1-3.
  • 26-35 kg: 7.5 ml once daily Days 1-3.
  • 36-45 kg: 10 ml once daily Days 1-3. Adults/older children: Use tablet form preferred; suspension for those unable to swallow tablets. Take on empty stomach (1 hour before or 2 hours after meals) for best absorption. Complete full course even if symptoms improve. Follow doctor/pharmacist instructions; do not adjust dose.

Common Side Effects:

• Gastrointestinal: Nausea, vomiting, diarrhoea, abdominal pain
• Headache
• Dizziness
• Rare: Allergic reactions (rash, swelling), liver enzyme elevation, QT prolongation (heart rhythm changes), Clostridium difficile diarrhoea Most mild/transient; serious rare: Severe allergic reactions, torsades de pointes (in QT-risk patients).

Package Type:

15 ml HDPE bottle (plastic; powder form; child-resistant cap; often in carton with measuring spoon/syringe and instructions).

Storage Advice: Store unreconstituted powder at room temperature (below 25-30°C), protected from moisture/light. After reconstitution: Refrigerate (2-8°C) and use within 10 days (or as labelled). Keep tightly closed. Keep out of reach of children.

Safety Advice:

• For bacterial infections only—ineffective for viral illnesses (e.g., common cold).
• Contraindicated in hypersensitivity to macrolides/azalides, or with drugs prolonging QT (e.g., certain antiarrhythmics).
• Caution in severe liver/renal impairment (dose adjustment), history of QT prolongation, myasthenia gravis (may exacerbate), or infants (monitor closely).
• Risk of QT prolongation—avoid in patients with known heart rhythm issues.
• Pregnancy/breastfeeding: Use if benefits outweigh risks (Category B).
• Interactions: Antacids (space 2 hours), warfarin (increased bleeding), digoxin (increased levels).
• Complete course to prevent resistance; report persistent/worsening symptoms or severe diarrhoea (C. diff risk).
• Stop if severe rash, fever, or irregular heartbeat occurs.

Product Substitutes: Other azithromycin suspensions in Ghana: Agycin (Bliss GVS variants), Zithromax Suspension (original Pfizer if available), or generics (e.g., 200 mg/5 ml or 100 mg/5 ml from importers like Cipla, Sun Pharma). Alternatives: Clarithromycin suspension, erythromycin, or amoxicillin (per infection/sensitivity)—consult paediatrician/pharmacist.

Manufacturer/Marketer:

Bliss GVS Pharma Ltd.

Country of Origin:

India.