Description

Amva-Denk 10/160 is a fixed-dose combination antihypertensive medication used to treat high blood pressure (essential hypertension). It contains two agents that work synergistically to relax blood vessels and reduce blood pressure, lowering the risk of heart attack, stroke, and kidney complications.

Prescription

Prescription-only medicine.

Therapeutic Category

• Cardiovascular agent
• Antihypertensive (Calcium Channel Blocker + Angiotensin II Receptor Blocker)
  

Active Ingredients/Composition

Each tablet contains:

• Amlodipine (as amlodipine besilate) – 10 mg
• Valsartan – 160 mg
  

Vitamins

• None

Minerals

• None

Variant

• Film-coated tablets
• Strength: 10 mg / 160 mg
• Other variants may include 5/80 mg, 5/160 mg, or 10/320 mg (depending on market availability).
  

Consume Type

• Oral tablet (swallowed whole with water, with or without food).
  

Directions/Usage

• Standard adult dose: 1 tablet once daily at the same time each day.
• May be taken with or without food.
• Dose may be adjusted by a doctor depending on blood pressure response.
• Not recommended for use in children under 18 years.
• Always take under medical supervision.
  

Common Side Effects

• Dizziness or lightheadedness (especially when starting treatment)
  Headache
• Swelling of ankles or feet (edema)
• Fatigue or flushing
• Nausea or abdominal pain
• Rare: low blood pressure, rapid heartbeat, muscle cramps, or elevated potassium levels
  

Package Type

• Blister packs (commonly 10 or 30 tablets per carton).
  

Storage Advice

• Store at room temperature (below 30 °C)
• Protect from moisture and direct sunlight
• Keep in original packaging until use
• Keep out of reach of children
  

Safety Advice

• Avoid during pregnancy and breastfeeding (risk to fetus).
• Caution in patients with liver, kidney, or heart failure.
  
• Avoid combining with potassium supplements or potassium-sparing diuretics (risk of hyperkalemia).
• Stand up slowly from sitting or lying positions to reduce dizziness.
• Regular monitoring of blood pressure, kidney function, and electrolytes is advised.
• Limit alcohol intake as it can enhance the hypotensive effect.
  

Product Substitutes

Other Amlodipine + Valsartan combination brands:

• Exforge
• Amlodac-V
• Amlovas-V
• Valz-AM
• Amlovasc V
  

Manufacturer/Marketer

• Denk Pharma GmbH & Co. KG – Germany.
• Distributed in multiple regions including Africa, Asia, and the Middle East through Denk Pharma’s international network.
  

Country of Origin

• Germany