Description:
Artenate DS 80/480 mg is a combination antimalarial drug used in the treatment of uncomplicated Plasmodium falciparum malaria, including strains resistant to other antimalarials. It combines two active agents: Artemether and Lumefantrine, which work synergistically to eliminate malaria parasites from the bloodstream.

Prescription:
Prescription-only medication (Rx) – not for self-medication

Therapeutic Category:
Antimalarial / Antiparasitic

Active Ingredients/Composition:

• Artemether – 80 mg

• Lumefantrine – 480 mg
  

Vitamins:
None

Minerals:
None

Variant:

• Commonly available as tablets

• Standard adult dose variant: 80/480 mg (Double Strength – DS)

• Pediatric/regular strength variant: 20/120 mg per tablet
  

Consume Type:
Oral (tablet)

Directions/Usage:

• Take with food, especially fatty foods to enhance absorption

• Typical adult dosing: 4 tablets initially, then again at 8 hours, and then twice daily for the next 2 days (total of 6 doses over 3 days)

• Always follow doctor’s instructions
  

Common Side Effects:

• Headache

• Dizziness

• Loss of appetite

• Weakness

• Nausea, vomiting, or abdominal pain

• Sleep disorders or palpitations (rare)

• Rare: serious allergic reactions or QT prolongation on ECG
  

Package Type:

• Blister pack of 6 or 12 tablets

• Labeled carton with dosage instructions
  

Storage Advice:

• Store below 30°C (86°F)

• Keep away from moisture and direct sunlight

• Keep out of reach of children
  

Safety Advice:

• Not recommended during first trimester of pregnancy, unless benefits outweigh risks

• Use with caution in patients with heart conditions (risk of QT prolongation)

• Complete full course to avoid resistance

• Avoid alcohol and self-medication

• Inform your doctor of any heart rhythm medications or other antimalarials
  

Product Substitutes:

• Coartem® (by Novartis – artemether/lumefantrine 20/120 mg)

• Falcynate-L

• Lonart DS

• Artefan
  (Brand names may vary by region)
  

Manufacturer/Marketer:
Multiple regional manufacturers—some common ones include:

• Ajanta Pharma

• Ipca Laboratories

• Emzor Pharmaceuticals

• Guilin Pharmaceutical (China)
  (Check packaging for specific brand)
  

Country of Origin:
Varies – commonly manufactured in India, Nigeria, China, and other malaria-endemic countries.