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Artesunate Injection 120mg

Artesunate Injection 120mg
Artesunate Injection 120mg - Image 2

Artesunate Injection 120mg

Artesunate Injection 120mg (Habinate 120 / Indasi or similar branding) is a fast-acting antimalarial medication containing artesunate, used for the initial treatment of severe malaria (including cerebral malaria) caused by Plasmodium falciparum. It rapidly reduces parasite load in the blood and is administered intravenously or intramuscularly in hospital/clinical settings. It is often part of artemisinin-based combination therapy (ACT) protocols for severe cases when oral treatment is not possible. In Ghana (Accra), artesunate 120mg injections (e.g., Habinate 120, Indasi, or generics) are common prescription antimalarials available in pharmacies/hospitals for emergency/severe malaria management.

Price: ₵25.00 /Pack

Key Product Information

Artemisinin Derivative / Antimalarial Agent (Rapid-acting blood schizonticide for severe malaria.

Injectable – Intravenous (IV) infusion or intramuscular (IM) injection (administered only by healthcare professionals; not for oral or self-administration).

Active ingredient: Artesunate – 120 mg per vial/ampoule (powder for reconstitution; yields ~20 mg/ml solution after dilution). Other ingredients (excipients): Sodium bicarbonate (solvent/diluent provided for reconstitution), sodium phosphate (buffer), and water for injection. The powder is white to off-white, sterile, and reconstituted to a clear solution for IV/IM use.

Glass vial or ampoule

Varies by batch (Habinate 120 / Indasi often by Indian manufacturers like Criticine Care, Iskon Remedies, or similar; registered generics). Marketed/distributed in Ghana by local importers/pharmacies (e.g., Scab Pharmacy, Country Medical Pharmacy).

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Product description

Description:

Artesunate Injection 120mg (Habinate 120 / Indasi or similar branding) is a fast-acting antimalarial medication containing artesunate, used for the initial treatment of severe malaria (including cerebral malaria) caused by Plasmodium falciparum. It rapidly reduces parasite load in the blood and is administered intravenously or intramuscularly in hospital/clinical settings. It is often part of artemisinin-based combination therapy (ACT) protocols for severe cases when oral treatment is not possible. In Ghana (Accra), artesunate 120mg injections (e.g., Habinate 120, Indasi, or generics) are common prescription antimalarials available in pharmacies/hospitals for emergency/severe malaria management.

Prescription:

Prescription-only (requires a doctor’s prescription in Ghana; administered by healthcare professionals in hospitals/clinics—never self-inject; not OTC due to injection route, malaria diagnosis requirements, and hypersensitivity risks).

Therapeutic Category:

Artemisinin Derivative / Antimalarial Agent (Rapid-acting blood schizonticide for severe malaria.

Active Ingredients/Composition:

  • Active ingredient: Artesunate – 120 mg per vial/ampoule (powder for reconstitution; yields ~20 mg/ml solution after dilution). Other ingredients (excipients): Sodium bicarbonate (solvent/diluent provided for reconstitution), sodium phosphate (buffer), and water for injection. The powder is white to off-white, sterile, and reconstituted to a clear solution for IV/IM use.

Vitamins: None.

Minerals: None.

Variant:

  • Artesunate Injection 120mg (Habinate 120 / Indasi or similar generics; standard 120mg vial/ampoule). Related variants: Artesunate 60mg (lower dose for children), Artesunate 200mg (higher dose), or other brands (e.g., Falcigo, Sunat, Skytem). The 120mg is the common adult/pediatric strength for severe malaria.

Consume Type:

Injectable – Intravenous (IV) infusion or intramuscular (IM) injection (administered only by healthcare professionals; not for oral or self-administration).

Directions/Usage:

Administered only in clinical settings by trained personnel (IV preferred for severe cases).

  • Adults and children: Standard WHO/Ghana protocol: 2.4 mg/kg IV/IM at 0 hours, 12 hours, 24 hours, then once daily until oral ACT can be tolerated (minimum 24 hours/3 doses; max 7 days parenteral).
    • Example (adult ~60kg): 144 mg (1.2 ml reconstituted) at 0, 12, 24 hours, then daily.
  • Reconstitute powder with provided solvent (e.g., 5% sodium bicarbonate); dilute further for IV infusion.
  • Follow with oral ACT (e.g., artemether-lumefantrine) as soon as possible.
  • Monitor patient for 30 minutes post-dose for hypersensitivity.

Common Side Effects: Common (mild):

  • Pain/redness at injection site (IM)
  • Nausea, vomiting
  • Headache, dizziness
  • Metallic taste
  • Anorexia, fatigue Rare/serious (seek immediate help): Hypersensitivity reactions (rash, itching, bronchospasm, anaphylaxis), hypotension, cardiac effects (QT prolongation rare), neurotoxicity (high doses), or hemolysis (in G6PD deficiency).

Package Type:

Glass vial or ampoule of 120mg powder (single-dose; often in packs of 1 or 6 vials/ampoules with solvent ampoules and tray; labeled carton with leaflet).

Storage Advice:

Store unopened vials at room temperature (below 25–30°C) in original packaging, away from direct sunlight and heat. Protect from light. Do not freeze. Reconstituted solution: Use immediately or as per label (usually within hours). Out of reach of children.

Safety Advice:

  • Administered only under medical supervision (risk of severe hypersensitivity—monitor for 30 minutes post-dose).
  • Contraindicated in hypersensitivity to artesunate/artemisinins.
  • Caution in pregnancy (first trimester use only if benefits outweigh risks), severe malaria in children, or G6PD deficiency (risk of hemolysis).
  • Follow national malaria treatment guidelines (Ghana uses ACTs; artesunate IV/IM for severe cases).
  • If allergic symptoms (rash, swelling, breathing difficulty) or severe hypotension occur during administration, stop immediately and treat urgently.
  • Keep out of reach of children (overdose risk).

Product Substitutes: Similar artesunate 120mg injections in Ghana include:

  • Generic artesunate 120mg injection (various importers).
  • Sunat 120mg Injection (artesunate).
  • Skytem 120mg Injection (artesunate).
  • Other brands like Falcigo, Artecrit, or local generics. Alternatives: Artesunate 60mg (lower dose), or quinine injection for severe malaria (consult doctor). Available at pharmacies/hospitals in Accra.

Manufacturer/Marketer:

Varies by batch (Habinate 120 / Indasi often by Indian manufacturers like Criticine Care, Iskon Remedies, or similar; registered generics). Marketed/distributed in Ghana by local importers/pharmacies (e.g., Scab Pharmacy, Country Medical Pharmacy).

Country of Origin:

India (primary source for Habinate 120 / Indasi artesunate 120mg injection imported to Ghana; BP/USP-compliant generics common in African markets).

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