Oral tablets: swallow with water. Usually taken with or after food to reduce stomach upset. 

– Example: For autoimmune conditions starting doses might be ~1–3 mg/kg/day; for transplant higher.

– Regular monitoring (blood counts, liver/renal function) is required. 

Safety Advice

 Do not use if hypersensitive to azathioprine. 

– Because it suppresses the immune system: increased risk of infection — monitor carefully. 

– Long-term use increases risk of certain cancers (e.g., lymphoma, skin cancer). 

– Use in pregnancy/breastfeeding only if strictly necessary and with specialist advice. 

– Avoid live vaccines while on therapy.

– Interacts with many drugs (e.g., allopurinol significantly increases toxicity) — check with your doctor/pharmacist.