Description: 

Caffeine Citrate Injection is used to treat neonatal apnea (premature infant breathing disorders).

Prescription: 

• Prescription-only (PO)

Dosage:

•  Neonates: 20-40 mg/kg (5-10 mg/mL) IV loading dose, followed by 5-10 mg/kg (2.5-5 mg/mL) IV maintenance dose

Therapeutic Category:

•  Respiratory Stimulant

Active Ingredients/Composition:

• Caffeine Citrate equivalent to 20 mg/mL Caffeine Base

Variant:

• Caffeine Citrate Injection (20mg/mL, 5mL, 10mL Amp)
• Caffeine Citrate Oral Solution (10mg/5mL)

Consume Type: 

• Intravenous Injection

Directions/Usage:

•  Administer IV slowly over 30 minutes
•  Monitor vital signs and respiratory status

Common Side Effects:

•  Tachycardia
•  Hypertension
•  Insomnia
• Jitteriness
•  Seizures (rare)

Package Type:

• Glass ampoules (5mL, 10mL)
• Cartons of 10 ampoules

Storage Advice:

• Store at 20-25°C (68-77°F)
•  Protect from light
•  Avoid freezing

Safety Advice:

• Monitor for signs of toxicity (seizures, cardiac arrhythmias)
• Consult healthcare professional before use
•  Discontinue use if adverse effects occur

Product Substitutes:

•  Cafcit (caffeine citrate) – Pfizer
•  Neo-Caf (caffeine citrate) – Upsher-Smith
•  Apnea-Caf (caffeine citrate) – Sandoz

Manufacturer/Marketer:

•  Pfizer Pharmaceuticals

Country of Origin:

• United States