Description

An oral antimalarial suspension combining artemether and lumefantrine, used to treat acute, uncomplicated malaria in children and adults.

 Prescription

Prescription-only 

Therapeutic Category

Antiprotozoal / antimalarial 

Active Ingredients / Composition

• Artemether 20 mg per 5 mL (total 240 mg per 60 mL)
• Lumefantrine 120 mg per 5 mL (total 1440 mg per 60 mL)
  

 Vitamins

None

Minerals

None

Variant

Oral powder to reconstitute into suspension; standard strength 20/120 mg per 5 mL, 60 mL bottle

Consumption type

Oral suspension

 Directions / Usage

• For patients ≥5 kg body weight
• Generally dosed twice daily for 3 days (dosing schedule depends on body weight) – exact regimen provided by prescriber or packaging
• Start treatment as early as possible after malaria is confirmed

Common Side Effects

• Possible side effects similar to artemether/lumefantrine: headache, dizziness, weakness, anorexia, abdominal pain, nausea, vomiting
• Monitor for allergic reactions and ECG changes (QT prolongation)
  

 Package Type

Powder in sachets or bottle for suspension; reconstituted into 60 mL glass or plastic bottle

Storage Advice

• Store powder and suspension in a cool, dry place
• Protect from light and moisture
• Use promptly after reconstitution; check local leaflet for expiry
  

Safety Advice

• Confirm malaria via RDT or microscopy before use
• Not for severe malaria cases—seek hospital management
• Check drug interactions (e.g., some antibiotics, HIV meds, heart rhythm medicines)
• Contraindicated in severe liver disease
• Monitor pregnant/lactating women and those with heart conditions
  

Product Substitutes

• Coartem® tablet or dispersible form (same artemether + lumefantrine)
• Generic artemether-lumefantrine suspension or tablets from other manufacturers
  

 Manufacturer / Marketer

• Active substance marketed by GBGL Pharma Limited; suspension produced by Ratnamani Healthcare Pvt. Ltd (India)
• Regional suppliers: Scab Pharmacy, Queen Street, Bonamour, etc. 

 Country of Origin

• India