Description:

Ceftazidime Injection is a broad-spectrum third-generation cephalosporin antibiotic used to treat serious bacterial infections. It is effective against Gram-negative bacteria (including Pseudomonas aeruginosa) and some Gram-positive organisms, commonly indicated for lower respiratory tract infections (e.g., pneumonia), urinary tract infections, skin/soft tissue infections, intra-abdominal infections, septicemia, meningitis, bone/joint infections, and gynecological infections. It is available as a powder for reconstitution and injection.

Prescription:

• Yes

Therapeutic Category:

• Antibiotic / Cephalosporin (Third Generation)

Active Ingredients/Composition:

• Ceftazidime (as ceftazidime pentahydrate) equivalent to 1000 mg (1 g) per via

Variant:

• Powder for solution for injection/infusion 1000 mg (1 g) per vial (standard strength; may be available in 250 mg, 500 mg, or 2 g in similar lines, but Johnlee commonly markets the 1 g variant as Seftaquick-1G or generic ceftazidime injection)

Consume Type:

• Parenteral (Intravenous infusion or slow IV injection; intramuscular in some cases)

Directions/Usage:

• Reconstitute with sterile water for injection, 0.9% sodium chloride, or 1% lidocaine (for IM use only). Administer by slow IV injection over 3-5 minutes or IV infusion over 15-30 minutes. Typical adult dosage: 1-2 g every 8-12 hours (up to 6 g/day in severe infections like meningitis or Pseudomonas). Dosage adjusted for renal impairment, age (pediatric weight-based), and infection severity. Use only under medical supervision; complete full course. Exact dosing and route determined by a healthcare professional.

Common Side Effects:

• Injection site reactions (pain, phlebitis, swelling), rash, pruritus (itching), diarrhea, nausea, vomiting, eosinophilia, elevated liver enzymes, or hypersensitivity reactions (e.g., urticaria). Less common: headache, dizziness, or superinfections (e.g., candidiasis).

Package Type:

• Single vial of powder

Storage Advice:

• Store unreconstituted vials at room temperature (below 25-30°C), protected from light. After reconstitution, use immediately or store refrigerated (2-8°C) and use within 24 hours (or as per label; discard if discolored). Keep out of reach of children.

Safety Advice:

• Prescription only; for professional administration. Contraindicated in known hypersensitivity to ceftazidime, other cephalosporins, or penicillins (cross-reactivity risk). Caution in patients with renal impairment (dose adjustment required), history of GI disease (e.g., colitis risk), or allergy history. Monitor for superinfections, Clostridium difficile-associated diarrhea, or allergic reactions (anaphylaxis possible). Not for viral infections. Safe in pregnancy (Category B) and breastfeeding when indicated, but consult doctor. Report severe diarrhea, rash, fever, or breathing difficulty immediately.

Product Substitutes:

• Fortaz or Tazicef (original brands ceftazidime)
• Seftaquick 1G (Johnlee’s branded ceftazidime)
• Generic Ceftazidime Injection 1 g (various brands like Ceftum, Cefta, or local generics)
• Other third-generation cephalosporins like cefotaxime or ceftriaxone for similar indications

Manufacturer/Marketer:

• Johnlee Pharmaceuticals Pvt. Ltd.

Country of Origin:

• India