Description

Ciprofloxacin Injection USP 100 ml is a broad-spectrum antibiotic belonging to the fluoroquinolone class. It is used to treat various bacterial infections in the respiratory tract, urinary tract, gastrointestinal tract, skin, soft tissue, and bones. The injectable form provides rapid delivery of the medicine directly into the bloodstream for serious or systemic infections.

Prescription

• Prescription-only medicine (POM)

Therapeutic Category

• Antibiotic / Antibacterial (Fluoroquinolone class)

Active Ingredients/Composition

Each 100 ml of injection contains:

• Ciprofloxacin (as Ciprofloxacin Lactate or Hydrochloride) – typically 200 mg per 100 ml (2 mg/ml concentration)
• Sodium chloride, lactic acid, and water for injection as excipients

Vitamins

• None

Minerals

• None

Variant

• Ciprofloxacin Injection USP 100 ml (200 mg/100 ml)
• Other variants: Ciprofloxacin Injection 200 mg/100 ml, 400 mg/200 ml, and Ciprofloxacin IV Infusion

Consume Type

• Parenteral (Intravenous infusion)
• Administered by IV infusion only under medical supervision

Directions/Usage

• Dosage depends on infection type and patient condition.
  • Typical adult dose: 200–400 mg every 12 hours, administered slowly IV over 60 minutes.
    
• Indications include: 
  • Respiratory tract infections
  • Urinary tract infections (complicated and uncomplicated)
  • Gastrointestinal infections (e.g., typhoid, salmonellosis)
  • Skin and soft tissue infections
  • Bone and joint infections
  • Septicemia and intra-abdominal infections
    

(Dosage and duration must be determined by a healthcare professional.)

Common Side Effects

Common and generally mild:

• Nausea or vomiting
  Diarrhea
• Headache or dizziness
• Local irritation at injection site
  Rare: Tendon pain, muscle weakness, allergic rash, or liver enzyme elevation
  

Package Type

• 100 ml sterile infusion bottle (glass or plastic IV bottle)
• Sealed with rubber stopper and aluminum cap
  

Storage Advice

• Store below 25°C.
• Do not freeze.
• Protect from light.
• Use immediately after opening.
  

Safety Advice

• For IV use only under professional supervision.
• Avoid use in children, pregnant, or breastfeeding women unless prescribed.
• Avoid use in patients with fluoroquinolone hypersensitivity.
• Use with caution in patients with renal or hepatic impairment.
• May cause tendinitis or tendon rupture (especially in elderly patients).
• Avoid simultaneous administration with calcium, magnesium, or iron supplements, as these may interfere with drug absorption (applies more to oral form).
• Discontinue immediately if allergic reaction or severe tendon pain occurs.
  

Product Substitutes

• Ciprobid IV (Ciprofloxacin)
• Ciplox IV (Cipla)
• Cifran IV (Ranbaxy/Sun Pharma)
• Baycip IV (Bayer)
• Ciprinol IV (KRKA)
  

Manufacturer/Marketer

Depending on brand and region, common manufacturers include:

• Bayer AG (Germany) – Original brand Cipro®
  Cipla Ltd. (India)
• Exeter Pharmaceuticals
• Sun Pharmaceutical Industries Ltd.
• Pfizer Laboratories

Country of Origin

• Germany (for Bayer)
  India, UK, or China for generic versions depending on manufacturer