Description

Clindamycin gel is a topical antibiotic medication used mainly for the treatment of acne vulgaris. It works by reducing the number of acne-causing bacteria (Cutibacterium acnes, formerly Propionibacterium acnes) and decreasing inflammation.

Prescription

Prescription-only medicine (Rx).

Therapeutic Category

• Antibiotic (Lincosamide class)
• Dermatological preparation
  

Active Ingredients/Composition

• Clindamycin phosphate (usually equivalent to 1% clindamycin base, in a 25 g gel tube).
  

Vitamins

• None

Minerals

• None

Variant

• Topical gel, 25 g tube
• May also be available in other strengths and as lotions or solutions (depending on manufacturer).
  

Consume Type

• External use only (topical application on skin).
  

Directions/Usage

• Apply a thin film of gel to the affected skin areas once or twice daily, as prescribed by a doctor.
• Wash the skin with mild soap, rinse, and dry before application.
• Avoid contact with eyes, mouth, or mucous membranes.
• Duration of use varies but may require 8–12 weeks for full benefit.
  

Common Side Effects

• Skin dryness
• Redness, itching, burning sensation
• Peeling of skin
• Oiliness of skin

Rare but serious: severe diarrhea or colitis (systemic absorption is minimal but possible).

Package Type

• 25 g laminated/aluminum tube, packaged in a carton.
  

Storage Advice

• Store at room temperature (below 25–30 °C)
• Do not freeze
• Keep the tube tightly closed and away from direct sunlight
• Keep out of reach of children
  

Safety Advice

• For external use only – do not ingest.
• Avoid prolonged sun exposure; use sunscreen if necessary.
• Do not apply to broken or eczematous skin unless prescribed.
• Discontinue if severe irritation or diarrhea occurs.
• Use in pregnancy or breastfeeding only under medical supervision.
• Not to be shared with others, even if they have similar symptoms. 

Product Substitutes

• Other topical clindamycin gels/lotions (generic versions). 
• Combination acne treatments such as: 
  • Clindamycin + Benzoyl Peroxide gel
  • Adapalene + Clindamycin gel
    
• Alternatives: Benzoyl peroxide, topical retinoids (adapalene, tretinoin), azelaic acid.
  

Manufacturer/Marketer

• “Pip Off” is a brand name; manufacturers may vary by region (different generic companies market it).
• Likely marketed by local/regional pharmaceutical companies in Africa/Asia.
  

Country of Origin

• Clindamycin was originally developed in the USA (Upjohn Company, 1960s).
• Pip Off brand is locally marketed; exact origin depends on the company (often India, Pakistan, or African distributors).