Description:

Duomal Suspension (also referred to as Duomal Syrup) 60ml by Luex is a pediatric-friendly oral antimalarial medication in liquid form. It is a fixed-dose combination used for the treatment of acute, uncomplicated malaria, primarily caused by Plasmodium falciparum, in children and patients who have difficulty swallowing tablets. It provides rapid parasite clearance through synergistic action of its components.

Prescription: Prescription-only (Rx). Requires confirmation of malaria diagnosis (e.g., via rapid test or microscopy) and a doctor’s prescription, following national malaria treatment guidelines (e.g., in Ghana).

Therapeutic Category:

Antimalarial / Artemisinin-based combination therapy (ACT).

Active Ingredients/Composition:

Artemether and Lumefantrine (exact concentration per 5ml or per bottle not uniformly specified in sources, but standard for such paediatric suspensions is often equivalent to dispersible tablet strengths, e.g., providing weight-based dosing similar to 20 mg artemether / 120 mg lumefantrine per dose unit; the 60ml bottle is formulated for reconstitution or ready-to-use suspension for multiple doses based on child weight).

Vitamins: None.

Minerals: None.

Variant: Paediatric suspension/syrup: 60ml bottle (designed for children; palatable formulation to aid administration in young patients).

Consume Type:

Oral (liquid suspension/syrup; shake well before use; administer with a measuring device/spoon).

Directions/Usage: Dosage is weight-based and follows a 3-day regimen (6 doses total), similar to standard artemether/lumefantrine guidelines:

• Administered twice daily (second dose 8 hours after first on Day 1, then morning/evening on Days 2-3).
• Must be taken with food or fatty milk to improve absorption.
• If vomiting occurs within 1-2 hours, repeat the dose.
• Exact volume per dose determined by child’s body weight (e.g., equivalent to standard paediatric dosing: for 5-<15 kg ~1 tablet equivalent, etc., adjusted to suspension strength). Always follow healthcare provider’s instructions or package insert for precise ml dosing. Complete the full course even if symptoms improve. Not for self-medication or prophylaxis.

Common Side Effects:

• Headache, dizziness
• Loss of appetite, nausea, vomiting
• Abdominal pain, fatigue/weakness
• Fever, muscle/joint pain Most are mild and transient. Rare serious effects include allergic reactions, heart rhythm changes (QT prolongation), or neurological issues—seek immediate medical attention if severe.

Package Type:

60ml bottle (plastic bottle with measuring cup or spoon; often requires shaking or specific preparation if powder for reconstitution).

Storage Advice: Store at room temperature (below 30°C), in a cool, dry place away from direct sunlight and heat. After opening or reconstitution (if applicable), follow label for shelf life (usually use within specified days). Keep out of reach of children.

Safety Advice:

• Take with food/fatty substance for better absorption and to reduce GI upset.
• Not for severe or complicated malaria (requires hospital treatment).
• Avoid in known hypersensitivity to components or certain heart conditions (QT prolongation risk).
• Consult doctor if pregnant/breastfeeding (generally acceptable in endemic areas under guidance), liver/kidney impairment, or concurrent medications.
• Complete full course to prevent resistance/recurrence. Monitor for worsening symptoms. Do not use for prevention. Professional diagnosis required.

Product Substitutes: Other artemether/lumefantrine pediatric suspensions or dispersible tablets like Coartem Dispersible, Lumartem Suspension, or generic AL suspensions (20/120 mg equivalents). Alternatives include other ACTs (e.g., artesunate-amodiaquine pediatric formulations)—follow local guidelines (e.g., Ghana NMCP) and doctor recommendation.

Manufacturer/Marketer:

Luex Healthcare

Country of Origin:

United Kingdom