Description
Esidrex tablets contain hydrochlorothiazide (HCTZ) 25 mg — a thiazide diuretic (“water-pill”) that increases urine output and helps lower blood pressure and reduce fluid overload.

Prescription
Yes — Esidrex is a prescription-only medicine (POM) in many regions.

Therapeutic Category
Thiazide diuretic / antihypertensive agent.

Active Ingredients / Composition

• Active: Hydrochlorothiazide (HCTZ) 25 mg per tablet. 
• Excipients: Depending on formulation; e.g., one Spanish leaflet lists lactose, wheat starch, magnesium stearate, colloidal silica. 
• No vitamins or minerals are part of the core active formulation.

Minerals
None declared as part of the formulation (though use of the drug may affect mineral balance in the body).

Variant
Tablet form, 25 mg strength (scored/‚sécable’ in some packs) — e.g., 30 or 90 tablet packs.

Consume Type
Oral. Swallow the tablet with water (with or without food, depending on clinician’s advice).

Directions / Usage

• Dose and frequency determined by doctor based on condition (hypertension, edema).
• Typically once daily in the morning to avoid nocturia (waking at night to urinate). 
• Take at same time each day. Follow your doctor’s instructions exactly.
  

Common Side Effects
Some of the more frequent side-effects include:

• Dizziness, light-headedness (especially on standing) due to fluid loss & lowered blood pressure. 
• Increased urination.
• Electrolyte disturbances (e.g., low potassium, sodium) leading to muscle cramps, weakness. 
• Photosensitivity (increased sun-sensitivity) and risk of skin reactions. 

Package Type
Typically blister-packs of tablets (e.g., 30 or 90 tablets) as per local regulatory packaging.

Storage Advice

 Store in original packaging, in a cool, dry place, protected from light and moisture. Keep out of reach of children. Check local label for exact temperature range.

Safety Advice

• Before taking, disclose to doctor if you have conditions like kidney disease, liver disease, gout, diabetes, lupus, or allergies to sulfonamide drugs. 
• Monitor electrolyte levels (potassium, sodium) and kidney/liver function during use.
• Avoid standing up quickly to prevent dizziness.
• Use sun-protection since photosensitivity is a risk.
• Because it increases urination, take dose earlier in the day to avoid disrupted sleep.
• If pregnant or breastfeeding, consult your physician regarding safety.
• This medicine reduces fluid and salt in the body — ensure adequate dietary intake of potassium if advised, and avoid dehydration.
  

Product Substitutes
Other tablets containing hydrochlorothiazide 25 mg (generic HCTZ) are alternatives under physician’s guidance. Brands such as “Esidrix” (US/GLOBAL) contain HCTZ.

Manufacturer / Marketer
In France for example: Novartis Pharma S.A.S. as manufacturer for Esidrex 25 mg.
Note: In other countries, licensed generics may be marketed by different companies.

Country of Origin
The French regulatory listing shows French origin for the marketed pack.
But in other regions (e.g., Ghana, Nigeria) the product may be imported or locally licensed — always check your local pack for origin.