Description:

Metoclopramide is a dopamine antagonist that enhances gastrointestinal motility and is primarily used to treat nausea and vomiting. It is available in various forms, including tablets, oral solutions, and injections.​

Prescription:

• Prescription-only medicine (POM)

Dosage:

• Adults: 
  • Oral Tablets/Solution: 10 mg up to three times daily. 
  • Injection: 10 mg administered slowly intravenously or intramuscularly, up to three times daily. 
  • Maximum Daily Dose: 30 mg or 0.5 mg/kg body weight. 
  • Maximum Treatment Duration: 5 days. 
• Paediatric Patients (1–18 years): 
  • Dose: 0.1–0.15 mg/kg body weight, up to three times daily. 
  • Maximum Daily Dose: 0.5 mg/kg body weight. 
  • Note: Contraindicated in children under 1 year of age.​

Therapeutic Category:

• Antiemetic and prokinetic agent.​

Active Ingredients/Composition:

• Each tablet contains 10 mg of metoclopramide hydrochloride anhydrous.

Variant:

• Tablets: 10 mg. 
• Oral Solution: 5 mg/5 ml. 
• Injection: 5 mg/ml. 

Consume Type:

• Oral (tablets and solution) and parenteral (intravenous or intramuscular injection).​

Directions/Usage:

• Administer doses before meals. 
• For injections, administer slowly over at least 3 minutes. 
• Do not exceed the recommended duration of treatment.​ 

Common Side Effects:

• Drowsiness. 
• Fatigue. 
• Diarrhoea. 
• Extrapyramidal symptoms (e.g., involuntary movements). 
• Restlessness. 
• Hypotension.​ 

Package Type:

• Available in blister packs for tablets, bottles for oral solutions, and ampoules for injections.​

Storage Advice:

• Store below 25°C. 
• Keep in the original packaging to protect from light. 
• Keep out of reach of children.​ 

Safety Advice:

• Use with caution in elderly patients and those with renal or hepatic impairment. 
• Monitor for signs of neurological side effects. 
• Avoid concurrent use with other drugs that increase the risk of extrapyramidal symptoms.​ 

Product Substitutes:

• Maxolon (metoclopramide hydrochloride). 
• Generic metoclopramide products available under various brand names.​ 

Manufacturer/Marketer:

• Amdipharm Mercury Company Limited.

Country of Origin:

• United Kingdom.