Description:

Myoxeril 10mg tablets is a centrally acting muscle relaxant. It is indicated for the short-term (typically up to 2-3 weeks) treatment of muscle spasms associated with acute, non-central (i.e., musculoskeletal) painful conditions, such as strains, sprains, or injuries. It reduces muscle spasm and related signs like pain, motor limitations, and restrictions in daily activities, usually as an adjunct to rest and physical therapy. The drug works primarily on the central nervous system (brainstem level) to relieve skeletal muscle hyperactivity without directly affecting muscle function or the neuromuscular junction.

Prescription: Prescription-only (Rx). Requires a doctor’s prescription due to its anticholinergic effects, potential for sedation, and risks (e.g., cardiac conduction issues). In Ghana and similar markets, it is regulated and available through pharmacies.

Therapeutic Category:

Skeletal muscle relaxant / Centrally acting muscle relaxant structurally related to tricyclic antidepressants but used for muscle relaxation).

Active Ingredients/Composition:

Active ingredient: Cyclobenzaprine hydrochloride 10 mg per film-coated tablet.

Vitamins: None.

Minerals: None.

Variant: 10 mg strength film-coated tablets (standard dose; pack of 20 tablets common in listings; no major variants noted beyond pack size).

Consume Type:

Oral (tablet; swallow whole with water; can be taken with or without food).

Directions/Usage: Adults: Recommended dose is 10 mg (1 tablet) three times daily. Dose range: 20-40 mg/day (2-4 tablets/day in divided doses), up to a maximum of 60 mg/day (6 tablets/day). Duration: Short-term only (should not exceed 3 weeks). Take as prescribed; follow doctor’s instructions precisely. Not recommended for children or long-term use without specialist oversight.

Common Side Effects:

• Drowsiness/sedation (common, dose-related)
• Dry mouth
• Dizziness, fatigue
• Constipation
• Blurred vision
• Headache Less common: Confusion, tachycardia, urinary retention, gastrointestinal upset. Serious rare: Arrhythmias, heart block, seizures, serotonin syndrome (if combined with certain drugs), hypersensitivity reactions.

Package Type:

Blister packs or strips of 20 film-coated tablets (often 2 x 10 or 20’s in carton; yellow film-coated tablets).

Storage Advice: Store at room temperature (below 25-30°C), in a cool, dry place away from direct sunlight, heat, and moisture. Keep in original packaging. Keep out of reach of children.

Safety Advice:

• Contraindicated in hypersensitivity to cyclobenzaprine or tricyclic compounds, recent myocardial infarction, arrhythmias, cardiac conduction abnormalities, congestive heart failure, hyperthyroidism, or use with MAOIs (or within 14 days of stopping MAOIs).
• Caution in elderly (higher risk of anticholinergic effects), glaucoma, urinary retention/prostate issues, liver impairment, or history of seizures.
• May cause drowsiness—avoid driving/machinery or alcohol.
• Risk of serotonin syndrome if combined with SSRIs, SNRIs, tramadol, etc.
• Pregnancy/breastfeeding: Use only if benefits outweigh risks (limited data).
• Do not exceed 3 weeks duration without reassessment.
• Report severe side effects (e.g., irregular heartbeat, confusion, severe dry mouth) promptly.

Product Substitutes: Other cyclobenzaprine 10mg tablets: Generic cyclobenzaprine (various importers), Flexeril (original, if available), or similar muscle relaxants like tizanidine (Zanaflex), baclofen, or methocarbamol. Consult doctor/pharmacist for equivalents based on indication (e.g., acute muscle spasm).

Manufacturer/Marketer:

Cross Pharm S.A. (marketing authorization holder; Swiss-based). Manufactured by The Madras Pharmaceuticals (India). Marketed/distributed in Africa (including Ghana) via local importers/pharmacies.

Country of Origin:

India.