Description:

Nystatin Oral Suspension is an antifungal medication used to treat and prevent candidal infections of the oral cavity, esophagus, and intestinal tract. It is particularly effective against Candida albicans, the primary cause of oral thrush. The suspension works by binding to fungal cell membranes, causing leakage of cellular contents and cell death. 

Prescription:

• Prescription-only medication.​

Dosage:

• Infants (1 month to 2 years): 1 ml dropped into the mouth four times daily.
  
• Children (≥2 years) and Adults: 1 ml dropped into the mouth four times daily; for intestinal candidiasis, adults may require 5 ml four times daily.
  
• Prophylaxis in Newborns: 1 ml once daily. The suspension should be kept in contact with affected areas as long as possible before swallowing. Treatment should continue for 48 hours after symptoms resolve to prevent relapse.

Therapeutic Category:

• Antifungal agent (Polyene macrolide antibiotic).

Active Ingredients/Composition:

• Active Ingredient: Nystatin.

• Excipients: Sucrose, sodium, propyl p-hydroxybenzoate, methyl p-hydroxybenzoate, sodium metabisulphite.
  

Variant:

• Available as an oral suspension, commonly in concentrations of 100,000 units/ml.​

Consume Type:

• Oral liquid suspension.​

Directions/Usage:

1. Shake the bottle well before use.
   
2. Measure the prescribed dose using a dosing syringe or dropper.
   
3. Administer the suspension directly into the mouth, ensuring it contacts the affected areas.
   
4. Hold the suspension in the mouth for as long as possible before swallowing.
   
5. Continue treatment for at least 48 hours after symptoms have resolved.
   

Common Side Effects:

• Nausea.
  
• Diarrhea.
  
• Abdominal pain.
  
• Rarely, allergic reactions such as rash, itching, or swelling.
  

Package Type:

• Typically supplied in amber glass or plastic bottles with a child-resistant cap, available in various volumes (e.g., 30 ml, 60 ml, 100 ml).​

Storage Advice:

• Store at room temperature (15°C to 25°C).
  
• Protect from light and moisture.
  
• Keep out of reach of children.​
  

Safety Advice:

• Not absorbed systemically; however, prolonged use may lead to overgrowth of non-susceptible organisms.
  
• Use with caution in patients with known hypersensitivity to nystatin or any component of the formulation.
  
• Consult a healthcare provider if symptoms persist or worsen after 14 days of treatment.
  

Product Substitutes:

• Mycostatin Oral Suspension.

• Nystan Oral Suspension.

• Nilstat Oral Suspension. These products contain the same active ingredient and are used for similar indications.​
  

Manufacturer/Marketer:

• Sandoz Limited

Country of Origin:

• United Kingdom