Description

P-Alaxin TS is an antimalarial medication used for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum (including multidrug-resistant strains). It contains dihydroartemisinin and piperaquine phosphate, which act synergistically to rapidly clear parasites and prevent recrudescence.

Prescription

Prescription-only medicine (Rx).

Therapeutic Category

• Antimalarial drug
• Artemisinin-based combination therapy (ACT)
  

Active Ingredients/Composition

Each tablet typically contains:

• Dihydroartemisinin – 40 mg
• Piperaquine phosphate – 320 mg

(DS = Double Strength formulation; 3’s indicates pack of 3 tablets).

Vitamins

• None

Minerals

• None

Variant

• Tablets (Double Strength, DS)
• Pack size: 3’s blister
  

Consume Type

• Oral tablets (swallowed with water)
  

Directions/Usage

• Standard adult regimen: 3 tablets taken as a single daily dose for 3 consecutive days (total of 9 tablets for full treatment course).
• Should be taken with water, preferably after food to improve absorption.
• Must complete the full course even if symptoms improve.
  

Common Side Effects

• Headache, dizziness
• Nausea, vomiting, abdominal pain, diarrhea
• Palpitations or QT prolongation (heart rhythm disturbance)
• Loss of appetite
• Fatigue or weakness
  

Package Type

• Blister pack of 3 tablets (carton packaging for stability and protection)
  

Storage Advice

• Store below 30°C in a cool, dry place
• Protect from moisture and direct sunlight
• Keep out of reach of children
  

Safety Advice

• Not recommended in patients with a history of QT prolongation or cardiac arrhythmias
• Use with caution in patients on other QT-prolonging medicines (e.g., macrolides, fluoroquinolones)
• Not for prophylaxis, only for treatment of acute malaria
• Avoid alcohol during treatment
• Consult a doctor if symptoms persist after completing treatment
  

Product Substitutes

Other ACT combinations:

• Coartem (Artemether/Lumefantrine)
• Eurartesim (Dihydroartemisinin/Piperaquine)
• Artequin (Artesunate + Mefloquine)
  

Manufacturer/Marketer

• Bliss GVS Pharma Ltd. (India) – well known for antimalarial formulations marketed in Africa and Asia under the P-Alaxin brand.
  

Country of Origin

• India (manufactured by Bliss GVS Pharma, exported to malaria-endemic regions, especially Africa).