Description
S‑Rocin is a 2% mupirocin cream, a topical antibiotic that kills certain bacteria by inhibiting isoleucyl‑tRNA synthetase, thus blocking protein synthesis. Used for skin infections like impetigo, boils, folliculitis, and minor infected wounds.
2. Prescription
- Prescription-only: It requires a doctor’s prescription and is administered under medical supervision
3. Therapeutic Category
- Belongs to topical antibiotics (ATC code D06AX09) intended for superficial bacterial skin infections
4. Active Ingredients / Composition
- Active: Mupirocin (as mupirocin calcium) – 20 mg/g (2% w/w)
- Inactive (typical): Benzyl alcohol, mineral oil, polyoxyl‑20 cetostearyl ether, phenoxyethanol, xanthan gum, mono‑ and diglycerides, glycerol monostearate, and purified water
5. Vitamins / Minerals
- None: As a topical antibiotic, it contains no vitamins or minerals.
- Variant
- Formulation: Cream (oil-in-water emulsion).
- Pack Sizes: Typically in 5 g, 10 g, 15 g, or 30 g tubes
7. Consume (Administration) Type
- Topical use only—apply to the skin; not for oral, ophthalmic, intranasal, or IV use .
- Directions / Usage
- Apply a small amount (with cotton swab/gauze) 3 times daily to clean, affected area for up to 10 days .
- Continue full course even if symptoms improve early
9. Common Side Effects
- Frequent: Local skin reactions—burning, stinging, itching, rash, pain, erythema, dryness, tenderness.
- Others: Headache, nausea.
- Rare: Allergic reactions—urticaria, angioedema; antibiotic-associated diarrhea (including C. difficile) .
10. Package Type
- Supplied in laminate or aluminium tubes, in sizes from 5 g to 30 g .
11. Storage Advice
- Store at room temperature (20–25 °C), protect from light and heat, and do not refrigerate or freeze ..
- Keep out of reach of children.
12. Safety Advice
- For topical use only, avoid mucous membranes and eyes.
- Discontinue if severe irritation or allergic reaction occurs; wash off and seek medical advice.
Prolonged use may cause fungal overgrowth or resistant bacteria—use only as prescribed.
- Pregnant and breastfeeding: considered safe; avoid applying to nipples during nursing unless washed off before feeding .
- In renal impairment or extensive burns, systemic absorption may increase—use caution .
13. Product Substitutes
Other topical antibiotics for similar skin infections include:
- Bactroban (mupirocin branded)
- Neosporin (Neomycin/Polymyxin/Bacitracin)
- Fusidic acid cream (e.g., Fucidin)
- Generic mupirocin (various brands) .
14. Manufacturer / Marketer
- Time Pharmaceuticals Ltd markets the brand ROCIN/S‑Rocin.
- Alternatives produced by companies like Aleor Dermaceuticals (India), Alembic Pharmaceuticals (India), Lincoln Pharmaceuticals (India) (under Dermocin), VCP Pharmaceutical (Vietnam), etc. .
15. Country of Origin
- ROCIN/S‑Rocin likely manufactured in India, via Time Pharmaceuticals.
- Other generic producers include India, Vietnam, and Bangladesh
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