Description:

Silverkant Cream (Silver Sulfadiazine Cream USP 1% w/w) is a topical antimicrobial agent used primarily to prevent and treat bacterial infections in second- and third-degree burns. It combines silver ions (with broad-spectrum antibacterial activity) and sulfadiazine (a sulfonamide antibiotic) to inhibit bacterial growth on burn wounds, reducing the risk of sepsis and promoting healing. It is commonly prescribed in burn care and available in Ghanaian pharmacies (e.g., in Accra) for wound management.

Prescription:

Prescription-only (requires a doctor’s prescription; often applied under medical supervision in hospitals or burn units, though dispensed in pharmacies with Rx in Ghana).

Therapeutic Category:

Topical Antibiotic / Antimicrobial / Sulfonamide (for burn wound infection prophylaxis and treatment

Active Ingredients/Composition:

• Active ingredient: Silver Sulfadiazine 1% w/w (10 mg/g). Other ingredients (excipients, typical for USP formulations): White petrolatum, stearyl alcohol, isopropyl myristate, sorbitan monooleate, polyoxyl 40 stearate, propylene glycol, water, and preservatives (exact list on label; may include methylparaben or others).

Vitamins: None.

Minerals:

Silver (from silver sulfadiazine; provides antimicrobial action but not a mineral supplement).

Variant:

• Silverkant 1% Cream (available in 30g or 50g tubes; the queried 50g is a common size). Related variants: Other silver sulfadiazine creams like Silverderma, SSD, Silvadene generics, or Flamazine (different branding but same 1% strength).

Consume Type:

Topical – Cream (applied externally to clean wounds; not for oral, ophthalmic, or internal use).

Directions/Usage: Clean the burn/wound area and debride necrotic tissue if needed (under medical guidance). Apply a thin layer (about 1.5–2 mm or 1/16 inch thick) to the affected area once or twice daily using sterile gloves or applicator. Cover with sterile dressing if required. Continue until healing or as directed (typically until the wound is ready for grafting or re-epithelialized). Do not apply to large areas without monitoring; consult doctor for dosage in children or extensive burns.

Common Side Effects:

• Local: Burning, stinging, pain, itching, rash, redness, or skin discoloration at application site.
• Other: Itching, peeling skin. Less common/serious (seek medical help): Leukopenia (low white blood cells), argyria (permanent silver staining of skin), allergic reactions (rash, swelling), or sulfonamide-related effects (fever, sore throat). Side effects are usually mild and transient.

Package Type:

Aluminum or plastic tube of 50g cream (some markets have 30g or 85g; often in carton with patient info).

Storage Advice:

Store at room temperature (below 25-30°C) in a cool, dry place, away from direct sunlight, heat, and freezing. Keep tightly closed and out of reach of children.

Safety Advice:

• For external use only; avoid eyes, mouth, mucous membranes.
• Contraindicated in premature infants, newborns <2 months, late pregnancy/breastfeeding near term (risk of kernicterus), or sulfonamide/silver allergy.
• Caution in G6PD deficiency (risk of hemolysis), liver/kidney impairment, or extensive burns (systemic absorption possible).
• Not for minor cuts/scrapes or non-burn wounds unless advised.
• Monitor blood counts if used long-term/large areas.
• Inform doctor if pregnant, breastfeeding, or on other medications.

Product Substitutes:

Other silver sulfadiazine 1% creams available in Ghana include:

• Silverderma 1% Cream (50g)
• Generic SSD/Silver Sulfadiazine (various importers)
• Flamazine or Silvadene generics. Alternatives (for burn care): Mupirocin (Bactroban), honey-based dressings, or povidone-iodine (if appropriate); consult doctor.

Manufacturer/Marketer:

 Health2000 or similar (Indian generic manufacturer, as seen in batch examples); marketed/distributed in Ghana by local importers/pharmacies (e.g., Vicdoris Pharmaceuticals Limited in Accra, or others like Pharma Xonline).

Country of Origin:

India