Description:

Skyclav 1.2g Injection (co-Amoxiclav)  is a combination antibiotic containing amoxicillin (a penicillin-type antibiotic) and clavulanic acid (a beta-lactamase inhibitor) in injectable form. It is used to treat a variety of bacterial infections, including respiratory tract infections (e.g., pneumonia, sinusitis), urinary tract infections, skin and soft tissue infections, intra-abdominal infections, bone and joint infections, and severe infections where beta-lactamase-producing bacteria may be involved. The 1.2g strength provides broad-spectrum coverage against many Gram-positive and Gram-negative bacteria.

Prescription:

• Yes

Therapeutic Category:

• Antibiotic / Penicillin with Beta-Lactamase Inhibitor

Active Ingredients/Composition:

• Amoxicillin 1000 mg (as sodium salt) + Clavulanic acid 200 mg (as potassium salt) per vial (total 1.2 g co-amoxiclav)

Vitamins: None

Minerals: None

Variant:

• 1.2 g powder for solution for injection/infusion (vial; standard 1000 mg/200 mg formulation)

Consume Type:

• Parenteral (Intravenous injection or infusion; may be given intramuscular in some cases)

Directions/Usage:

• Reconstitute the powder with 20 ml Water for Injections or 0.9% sodium chloride solution. Administer by slow IV injection over 3-4 minutes or IV infusion over 30-60 minutes. Typical adult dosage: 1.2 g every 8 hours (or every 6 hours for severe infections). Dosage adjusted for children based on weight (e.g., 30 mg/kg/day divided doses). Use only under medical supervision; complete full course as prescribed. Not for self-administration.

Common Side Effects:

• Diarrhea, nausea, vomiting, rash, itching, candidiasis (thrush), injection site reactions (pain, phlebitis). Less common: headache, dizziness, abdominal pain.

Package Type:

• Single vial of powder (often supplied with or without diluent; packs of 1 vial or multiples in boxes)

Storage Advice:

• Store unreconstituted vials in a cool, dry place below 25-30°C, protected from light. After reconstitution, use immediately or store refrigerated (2-8°C) and use within specified time (usually 4-8 hours depending on diluent). Keep out of reach of children.

Safety Advice:

• Prescription only; for professional administration. Contraindicated in patients with hypersensitivity to penicillins, cephalosporins, or beta-lactamase inhibitors. Caution in patients with history of allergic reactions, liver/kidney impairment, or glandular fever (risk of rash). Risk of serious allergic reactions (anaphylaxis) or Clostridium difficile-associated diarrhea. Monitor for superinfections. Consult doctor if pregnant, breastfeeding, or on other medications (e.g., anticoagulants). Not for viral infections.

Product Substitutes:

• Augmentin 1.2 g Injection (GSK)
• Amoksiklav 1.2 g Injection
• Clavam 1.2 g Injection
• Generic Co-Amoxiclav 1.2 g Injection (various brands like Bedimox, Clavcan, Exoclav)

Manufacturer/Marketer:

• Eskay

Country of Origin:

• India