Description:
Vivon DS 80/480 mg is a double-strength fixed-dose combination antimalarial tablet used for the treatment of uncomplicated Plasmodium falciparum malaria. It contains artemether and lumefantrine, which work synergistically to eliminate blood-stage malaria parasites and reduce the risk of recurrence.

Prescription:
Prescription-only (Rx) – Must be used under a healthcare provider’s supervision.

Therapeutic Category:
Antimalarial / Antiparasitic

Active Ingredients/Composition:

• Artemether – 80 mg

• Lumefantrine – 480 mg
  

Vitamins:
None

Minerals:
None

Variant:

• Vivon DS (Double Strength) 80/480 mg

• Standard strength version: Vivon 20/120 mg for pediatric or low-weight patients
  

Consume Type:
Oral tablet

Directions/Usage:

• Take with food, preferably a fatty meal to increase absorption.

• Adult dosage (based on DS formulation):
  • 1 tablet initially, then

  • 1 tablet after 8 hours, followed by

  • 1 tablet twice daily for the next 2 days (Total: 6 tablets in 3 days)

• Dosage may be adjusted based on weight and clinical condition.

• Always complete the full course, even if symptoms improve.
  

Common Side Effects:

• Nausea

• Vomiting

• Headache

• Dizziness

• Abdominal discomfort

• Sleep disturbances

• Rare: allergic reactions or ECG changes (QT prolongation)
  

Package Type:

• Blister packs of 6 tablets

• Labeled carton with usage instructions

Storage Advice:

• Store below 30°C (86°F)

• Protect from light and moisture

• Keep out of reach of children
  

Safety Advice:

• Avoid in first trimester of pregnancy, unless benefits outweigh risks

• Use cautiously in people with heart conditions or those on QT-prolonging medications

• Not recommended for use in children under 5 kg or under 12 years unless prescribed

• Avoid missed doses to prevent resistance

• Do not use for malaria prophylaxis or prevention
  

Product Substitutes:

• Coartem DS (Novartis)

• Lonart DS

• Amatem Forte

• Falcynate DS

• Artefan DS

• Other artemether/lumefantrine DS formulations
  

Manufacturer/Marketer:
Vivon is commonly marketed by regional pharmaceutical companies (such as in Nigeria, Ghana, or other malaria-endemic areas). Exact manufacturer can be confirmed via packaging.

Country of Origin:
Often manufactured in India, Nigeria, or other African countries, depending on the licensing arrangement.