Description:

Amciclox Oral Suspension 100ml (by Letap Pharmaceuticals) is a combination antibiotic syrup containing amoxicillin (a broad-spectrum penicillin) and cloxacillin (a penicillinase-resistant penicillin). It is used to treat bacterial infections caused by susceptible organisms, particularly those that may produce beta-lactamase enzymes (e.g., mixed staphylococcal and streptococcal infections). Common indications include respiratory tract infections (e.g., tonsillitis, sinusitis, bronchitis, pneumonia), skin and soft tissue infections, ear infections (otitis media), urinary tract infections, and dental infections. The suspension form is convenient for children and adults who have difficulty swallowing tablets. It is a widely available, affordable prescription antibiotic in Ghanaian pharmacies (e.g., in Accra at Scab Pharmacy, Country Medical Pharmacy, Beybee Pharmacy, Meldinpharma).

Prescription:

Prescription-only (requires a doctor’s prescription in Ghana; dispensed by pharmacies with Rx to confirm bacterial infection and appropriate use, avoiding misuse/resistance).

Therapeutic Category:

Broad-Spectrum Penicillin Antibiotic Combination (Beta-lactamase resistant; for mixed bacterial infections;or similar for amoxicillin + cloxacillin).

Active Ingredients/Composition:

Per 5 ml (after reconstitution):

• Amoxicillin (as amoxicillin trihydrate) – 125 mg
• Cloxacillin (as cloxacillin sodium) – 125 mg Total 250 mg/5 ml (125 mg amoxicillin + 125 mg cloxacillin per 5 ml). Other ingredients (excipients, typical): Sucrose/sorbitol (sweetener), flavoring (e.g., fruit), preservatives (e.g., sodium benzoate), suspending agents, thickeners, citric acid (pH adjuster), and purified water (powder for reconstitution).

Vitamins: None.

Minerals: None.

Variant:

• Amciclox Oral Suspension 100ml (standard 125 mg/125 mg per 5 ml strength after reconstitution). Related variants: Amciclox 250mg/250mg per 5 ml (higher strength in some markets), Amciclox Capsules/Tablets (solid form, e.g., 250mg/250mg or 500mg/500mg), or Amciclox Dry Syrup in different volumes (e.g., 60ml). The 100ml bottle is common for pediatric/adult use.

Consume Type:

Oral – Powder for oral suspension (reconstitute with water to make liquid; shake well before each dose; measured with provided syringe/spoon).

Directions/Usage:

Reconstitute powder with specified boiled/cooled water volume (usually ~90–95 ml for 100ml final volume; follow bottle instructions). Shake vigorously.

• Adults: Typically 10 ml (500 mg total antibiotic) every 6–8 hours (3–4 times daily).
• Children: Weight-based (e.g., 20–40 mg/kg/day divided every 6–8 hours; doctor determines exact).
• Take at start of meals to reduce stomach upset.
• Duration: Usually 5–10 days (complete full course even if symptoms improve). Use measuring device (not household spoon). Store reconstituted suspension in refrigerator.

Common Side Effects: Common:

• Gastrointestinal: Diarrhea, nausea, vomiting, abdominal pain.
• Skin: Rash, itching (allergic reaction risk).
• Other: Candidiasis (thrush). Rare/serious (seek immediate help): Severe diarrhea (C. difficile), allergic reactions (hives, swelling, anaphylaxis), liver issues (jaundice), or blood disorders.

Package Type:

Amber plastic bottle of 100ml (powder for reconstitution; child-resistant cap, measuring syringe/spoon included; often in carton with leaflet).

Storage Advice:

• Before reconstitution: Store dry powder below 25–30°C in cool, dry place, away from light/moisture.
• After reconstitution: Refrigerate (2–8°C); do not freeze. Use within 7–14 days (check label). Shake well before each dose. Out of reach of children.

Safety Advice:

• Only for bacterial infections (ineffective against viruses).
• Contraindicated if allergic to penicillins/cephalosporins or ingredients.
• Caution in renal impairment (dose adjustment), history of colitis, or infectious mononucleosis (higher rash risk).
• Inform doctor if pregnant/breastfeeding (generally safe but confirm), or on anticoagulants (may increase bleeding risk).
• If severe rash, breathing difficulty, or persistent diarrhea occurs, stop and seek urgent care.
• Complete course to prevent resistance; probiotics may help prevent diarrhea.

Product Substitutes: Similar amoxicillin + cloxacillin oral suspensions in Ghana include:

• Generic amoxicillin/cloxacillin dry syrup 125mg/125mg per 5ml (various importers).
• Ampiclox (Beecham/GSK brand, similar combo).
• Other brands like Amclox, Cloxamox, or local generics. Alternatives: Amoxicillin-clavulanate (Augmentin generics) or other cephalosporins (consult doctor for infection/sensitivity). Available at pharmacies like Scab Pharmacy, Country Medical Pharmacy in Accra.

Manufacturer/Marketer:

Letap Pharmaceuticals Limited (Ghana-based; produces Amciclox as part of its antibiotic range). Marketed/distributed locally in Ghana by Letap (address: Plot 107, Graphic Road, South Industrial Area, Accra).

Country of Origin:

Ghana (manufactured locally by Letap Pharmaceuticals Ltd.; widely stocked in Accra pharmacies as a local product).