Description:

•  An anti-migraine tablet combining an ergot alkaloid with a stimulant to constrict widened blood vessels in the brain during an active headache attack. 

Prescription:

•  Prescription Only Medicine (POM). 

Therapeutic Category:

•  Antimigraine Agent / Ergot Alkaloid Derivatives. 

Active Ingredients/Composition:

•  Each tablet contains 1 mg Ergotamine Tartrate (vasoconstrictor) and 100 mg Caffeine Anhydrous (enhances ergotamine absorption). 

Variant: 

• Standard 1mg/100mg oral tablet. 

Consume Type:

•  Oral use only (swallowed whole with water at the immediate onset of an attack). 

Directions/Usage:

• Take 1 to 2 tablets immediately at the first sign of a migraine attack.
• If the headache persists, take 1 additional tablet every 30 to 60 minutes.
• Strict Limits: Do not exceed 6 tablets per attack/day and no more than 10 tablets in a single week. 

Common Side Effects: 

• Nausea, vomiting, dizziness, elevated blood pressure, abdominal pain, or numbness/tingling in the fingers and toes (due to peripheral vasoconstriction).

Package Type:

•  Cardboard box containing blister packs of 30 tablets. 

Storage Advice:

•  Store below 25°C in a dry place. Protect completely from light and moisture. Keep out of reach of children. 

Safety Advice:

•  Black Box Warning: Concomitant use with potent CYP3A4 inhibitors (e.g., macrolide antibiotics like erythromycin, or azole antifungals like ketoconazole) is strictly contraindicated, as it can cause dangerous, life-threatening peripheral ischemia (vasospasm/restricted blood flow). Contraindicated during pregnancy, breastfeeding, and in patients with peripheral vascular disease, coronary heart disease, or severe liver/kidney failure. 

Manufacturer/Marketer:

•  Marketed and distributed by Assos Pharmaceuticals. 

Country of Origin: 

• Türkiye (Turkey).