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Casodex Tablets

Casodex Tablets
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Casodex Tablets

Casodex is an oral non-steroidal anti-androgen used in the management of prostate cancer. It works by binding to androgen receptors and blocking the action of testosterone, thereby slowing the growth and spread of prostate cancer cells.

Price: Price range: ₵32.21 through ₵92.82 /Tablet

Key Product Information

Antineoplastic / Hormonal therapy Anti-androgen

Oral tablets, swallowed whole with water, with or without food

Bicalutamide Casodex 50 mg tablet Casodex 150 mg tablet

Blister packs, typically 28 or 30 tablets per carton

AstraZeneca (original developer and global marketer).

United Kingdom
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Product description

 Description

Casodex is an oral non-steroidal anti-androgen used in the management of prostate cancer. It works by binding to androgen receptors and blocking the action of testosterone, thereby slowing the growth and spread of prostate cancer cells.

Prescription

Prescription-only medicine (Rx).

Therapeutic Category

  • Antineoplastic / Hormonal therapy
  • Anti-androgen

Active Ingredients/Composition

  • Bicalutamide
    • Casodex 50 mg tablet
    • Casodex 150 mg tablet

Vitamins

  • None

Minerals

  • None

Variant

  • Tablets available in strengths:
    • 50 mg
    • 150 mg

Consume Type

  • Oral tablets, swallowed whole with water, with or without food

Directions/Usage

  • Casodex 50 mg: Usually taken once daily in combination with a luteinizing hormone-releasing hormone (LHRH) analogue or surgical castration for advanced prostate cancer. 
  • Casodex 150 mg: May be used once daily as monotherapy in certain prostate cancer cases (e.g., locally advanced disease when surgery or other therapy is not appropriate).
  • Dose and duration depend on stage of cancer and doctor’s recommendation.

Common Side Effects

  • Hot flashes
  • Breast tenderness or enlargement (gynecomastia)
  • Decreased libido, erectile dysfunction
  • Gastrointestinal upset (nausea, constipation, diarrhea)
  • Fatigue, dizziness
  • Anemia
  • Liver enzyme elevation (rarely, severe liver injury)

Package Type

  • Blister packs, typically 28 or 30 tablets per carton

Storage Advice

  • Store at room temperature (below 30 °C)
  • Protect from light and moisture
  • Keep out of reach of children

Safety Advice

  • Regular monitoring of liver function tests is required.
  • May cause dizziness; caution when driving or operating machinery.
  • Not for use in women or children.
  • Contraindicated in patients with severe liver impairment or known hypersensitivity to bicalutamide.
  • Avoid concomitant use with warfarin (increases anticoagulant effect).
  • Long-term use requires monitoring for bone health and cardiovascular risk.

Product Substitutes

  • Other brands of Bicalutamide (generic equivalents)
  • Alternative anti-androgens: Flutamide, Nilutamide, Enzalutamide
  • Other prostate cancer therapies: Abiraterone, GnRH analogues (Leuprolide, Goserelin), Orchiectomy

Manufacturer/Marketer

  • AstraZeneca (original developer and global marketer).

Country of Origin

  • Originally developed in the United Kingdom (AstraZeneca, formerly Zeneca Pharmaceuticals).
  • Now manufactured globally under license and also available as generics. 

 

Additional information

Additional information

Dosage

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