Description:

 An oral allopathic tablet used to treat high blood pressure and ease urinary difficulties caused by an enlarged prostate gland.

Prescription:

 Prescription Only Medicine (POM)

Therapeutic Category:

 Alpha-1 Adrenergic Antagonist (commonly known as an Alpha-Blocker). 

Active Ingredients/Composition:

• 2mg Variant: Contains 2.42 mg Doxazosin Mesilate, equivalent to 2mg of active doxazosin.
• 4mg Variant: Contains 4.84 mg Doxazosin Mesilate, equivalent to 4mg of active doxazosin.
• Excipient note: Contains Lactose (24mg in the 2mg tablet; 48mg in the 4mg tablet). 

Variant: 2mg (white, capsule/caplet-shaped uncoated tablet) and 4mg (white, diamond-shaped uncoated tablet) strengths. Both strengths feature a break line and can be divided into equal halves. 

Consume Type: 

Oral use only (swallowed whole with water). 

Directions/Usage:

• Take one tablet daily at roughly the same time, either in the morning or evening, with or without food.
• Dosing Protocol: The starting dose is always 1mg once daily to prevent a drastic, dangerous drop in blood pressure. Your doctor will gradually step up your dose to 2mg, 4mg, or up to a maximum of 16mg over several weeks based on clinical response.
• Crucial Rule: If you miss your doses or stop taking doxazosin for a few days, do not restart at the 2mg or 4mg dose. You must consult your doctor to step back down and re-titrate from the 1mg baseline. 

Common Side Effects: 

Postural hypotension (dizziness or fainting upon standing up quickly), fatigue, drowsiness, headache, palpitations (racing heart), fluid retention (swollen feet or ankles), respiratory infections (bronchitis/cough), and nasal congestion. [

Package Type: 

Aluminum-PVC blister sheets enclosed in a retail cardboard dispensing carton containing 28 or 30 tablets. 

Storage Advice:

 Store in the original package below 25°C to protect the uncoated tablets from excess ambient moisture and light degradation. Keep out of sight and reach of children. 

Safety Advice:

• First-Dose Phenomenon: Doxazosin can cause sudden fainting or extreme lightheadedness after the very first dose or after a dose escalation. It is highly advised to take your first dose at bedtime.
• Surgical Warning: If you are scheduled for cataract eye surgery, inform your ophthalmologist that you take an alpha-blocker, as it can cause Intraoperative Floppy Iris Syndrome (IFIS) during the procedure.
• Interactions: Use extreme caution when taking erectile dysfunction medications (PDE-5 inhibitors like sildenafil or tadalafil), as combining them can cause severe, symptomatic drops in blood pressure. 

Manufacturer/Marketer: 

Manufactured and distributed by Milpharm Limited (Aurobindo Pharma UK).

Country of Origin

United Kingdom (UK) / India.