Description:

Ephedrine Nasal Drops 0.5% w/v 10ml is a topical nasal decongestant used for the temporary relief of nasal congestion associated with the common cold, hay fever, sinusitis, rhinitis, and upper respiratory allergies. It works as a sympathomimetic agent that constricts blood vessels in the nasal mucosa, reducing swelling and congestion to improve breathing.

Prescription:

Over-the-counter (OTC) in Ghana.

Therapeutic Category:

Topical Nasal Decongestant (Sympathomimetic / Alpha-adrenergic agonist).

Active Ingredients/Composition:

• Ephedrine Hydrochloride 0.5% w/v (5 mg per ml) Other typical ingredients: Sodium chloride (for isotonicity), preservatives (e.g., benzalkonium chloride or sodium metabisulfite), and purified water. The solution is clear and colourless.

Vitamins: None.

Minerals: None (sodium chloride is present as an excipient for tonicity).

Variant:

• Ephedrine Nasal Drops 0.5% w/v 10ml (standard adult strength). Related variants: 1% strength (stronger, usually for adults only) and paediatric formulations (lower strength or different brands). The 0.5% is the common milder version.

Consume Type:

Nasal – Topical nasal drops (instilled into the nostrils; not for oral or injectable use).

Directions/Usage:

• Adults and children over 12 years: Instil 1–3 drops into each nostril, up to 3–4 times daily.
• Children under 12 years: Use only on doctor’s advice (lower frequency or paediatric strength preferred).
• Do not use for more than 5–7 consecutive days to avoid rebound congestion.
• Tilt head slightly back, instil drops, and keep head tilted for a few moments. Blow nose gently if needed after a few minutes.

Common Side Effects: Common (local):

• Temporary stinging, burning, or dryness in the nose.
• Sneezing.
• Rebound congestion (rhinitis medicamentosa) if used longer than 7 days.

Less common: Headache, restlessness, or mild increase in blood pressure with excessive use.

Package Type:

10ml plastic dropper bottle with screw cap (usually in a carton with patient information leaflet).

Storage Advice: Store at room temperature (below 25–30°C) in a cool, dry place, away from direct sunlight and heat. Keep the bottle tightly closed. Do not freeze. Discard any unused contents 28 days after opening or by the expiry date.

Safety Advice:

• For nasal use only. Avoid contact with eyes.
• Do not use if you have narrow-angle glaucoma, severe hypertension, heart disease, hyperthyroidism, or are taking MAO inhibitors (or within 14 days of stopping them).
• Caution in pregnancy, breastfeeding, diabetes, or prostate enlargement.
• Prolonged or frequent use can cause rebound congestion (worse blockage after stopping).
• Stop use and consult a doctor if symptoms persist beyond 7 days, worsen, or if you experience severe side effects.
• Keep out of reach of children.

Product Substitutes: Common substitutes in Ghana include:

• Other ephedrine nasal drops (various local brands).
• Xylometazoline nasal drops (e.g., Otrivin).
• Oxymetazoline nasal sprays/drops.
• Saline nasal drops (for milder or paediatric use). Consult a pharmacist in Accra for suitable alternatives based on age and condition.

Manufacturer/Marketer:

Aspen Pharmacare.

Country of Origin:

South Africa / Ghana (manufactured by Aspen or its Ghanaian affiliate; widely available as an imported or locally produced product in Ghanaian pharmacies).