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Gelofusine Injection

Gelofusine Injection

Gelofusine is an intravenous colloid solution containing 4% succinylated gelatin, used to replace lost blood volume and improve circulation in patients experiencing hypovolemia due to hemorrhage, trauma, or surgery.

Price: 300.00

Key Product Information

Plasma volume expander (colloid). ​

Administered via intravenous infusion.

Each 1000 mL of Gelofusine contains:​ Succinylated gelatin (modified fluid gelatin): 40 g​ Sodium chloride: 7 g​ Sodium hydroxide (for pH adjustment)​ Water for injections

Vial

B. Braun Medical. ​

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Product description

Description:

Gelofusine is an intravenous colloid solution containing 4% succinylated gelatin, used to replace lost blood volume and improve circulation in patients experiencing hypovolemia due to hemorrhage, trauma, or surgery.

Prescription:

Gelofusine is a prescription-only medication and should be administered under the supervision of a healthcare professional.

Therapeutic Category:

Plasma volume expander (colloid).

Active Ingredients/Composition:

Each 1000 mL of Gelofusine contains:

  • Succinylated gelatin (modified fluid gelatin): 40 g

  • Sodium chloride: 7 g

  • Sodium hydroxide (for pH adjustment)

  • Water for injections

Vitamins:

Gelofusine does not contain any vitamins.

Minerals:

Gelofusine contains sodium and chloride ions due to the presence of sodium chloride.

Variant:

Gelofusine is available as a 4% solution for intravenous infusion.

Consume Type:

Administered via intravenous infusion.

Directions/Usage:

The dosage of Gelofusine is adjusted according to the patient’s blood loss and individual needs to restore and maintain stable hemodynamic status. Typically, 500 to 1000 mL is administered initially, with higher doses for severe blood loss. The infusion rate depends on the patient’s condition and response to treatment.

Common Side Effects:

While generally well-tolerated, Gelofusine may cause:

  • Allergic reactions, including anaphylactoid/anaphylactic reactions of varying severity.

  • Nausea, vomiting, and abdominal pain.

  • Decreased oxygen saturation.

  • Decreased hematocrit and plasma protein levels due to hemodilution.

Package Type:

Gelofusine is supplied in 500 mL Ecoflac® plus and Ecobag® containers.

Storage Advice:

Store Gelofusine at controlled room temperature, away from direct sunlight and freezing conditions. Keep the product in its original packaging until use.

Safety Advice:

  • Hypersensitivity: Monitor patients for signs of allergic reactions during and after administration.

  • Hemodilution: Carefully monitor hematocrit and plasma protein levels to avoid excessive dilution.

  • Fluid Overload: Use with caution in patients with conditions that may be exacerbated by increased circulatory volume, such as heart failure or renal impairment.

  • Compatibility: Gelofusine is compatible with blood and blood products; however, always ensure compatibility before co-administration.

Product Substitutes:

Alternative plasma volume expanders include other gelatin-based solutions like Gelaspan, as well as starch-based colloids and albumin solutions. The choice of substitute depends on the clinical situation and patient-specific factors.

Manufacturer/Marketer:

Gelofusine is manufactured and marketed by B. Braun Medical.

Additional information

Additional information

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