Description

Hypertonic Saline Injection is a sterile solution used to treat severe hyponatremia (low sodium levels), increased intracranial pressure, and other conditions requiring rapid correction of sodium levels.

Prescription

• Prescription-only medicine (POM)

Dosage

•  Initial dose: 30-100mL (3-10%) IV over 3-5 minutes
•  Maintenance dose: 10-50mL (1-5%) IV every 2-4 hours as needed

Therapeutic Category

• Electrolyte replenisher, Osmotic diuretic

Active Ingredients/Composition

•  Sodium chloride 3%, 5%, or 10% w/v solution
•  Other ingredients: Water for injection, Sodium hydroxide (for pH adjustment)

Variant

•  Hypertonic Saline 3%
•  Hypertonic Saline 5%
•  Hypertonic Saline 10%
•  Hypertonic Saline 23.4%

Consume Type

• Intravenous (IV) injection

Directions/Usage

•  Administer IV over 3-5 minutes.
•  Monitor sodium levels, blood pressure, and fluid status.

Common Side Effects

•  Fluid overload
•  Hypokalemia (low potassium levels)
•  Hypernatremia (high sodium levels)
•  Seizures
•  Coma

Package Type

• Vial or ampoule containing 10mL, 20mL, or 50mL solution

Storage Advice

•  Store at room temperature (15-30°C/59-86°F).
•  Protect from light and heat sources.
•  Keep out of reach of children.

Safety Advice

•  Use as directed by a healthcare professional.
• Monitor sodium levels, blood pressure, and fluid status regularly.
•  Be aware of signs of fluid overload, such as shortness of breath, chest pain, and swelling.

Product Substitutes

•  Other electrolyte replenishers (e.g., sodium lactate, potassium chloride)
•  Other osmotic diuretics (e.g., mannitol, urea)

Manufacturer/Marketer

•  Pfizer

Country of Origin

• USA