Description

Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve moderate to severe pain, inflammation, and stiffness associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gouty arthritis, bursitis, and tendinitis. It works by inhibiting the production of prostaglandins, substances in the body that cause inflammation and pain.

Prescription

• Status: Prescription-only medicine (POM).
  

Therapeutic Category

• Class: Nonsteroidal Anti-Inflammatory Drug (NSAID).
  

Active Ingredients/Composition

• Indomethacin USP: 25 mg per capsule.
  

Vitamins

• None.

 Minerals

• None.
  

Variant

• Form: Hard gelatin capsule.
• Dosage Strength: 25 mg.
• Appearance: Capsules may vary in color and imprint depending on the manufacturer (e.g., light green opaque capsules imprinted with “TEVA 4029” or “G406”).

Consume Type

• Oral administration.
  

Directions/Usage

• Dosage: As prescribed by a healthcare professional.
• Administration: Swallow the capsule whole with water; do not crush or chew.
• Timing: It is recommended to take with food, milk, or an antacid to minimize gastrointestinal discomfort.
  

 Common Side Effects

• Gastrointestinal issues: nausea, vomiting, indigestion, diarrhea, constipation.
• Central nervous system effects: headache, dizziness, drowsiness.
• Others: ringing in the ears (tinnitus), rash, itching.
  

Package Type

• Packaging: Available in bottles or blister packs containing various quantities (e.g., 15, 30, 60, 100, or 1000 capsules), depending on the manufacturer.

Storage Advice

• Store at controlled room temperature: 20°C to 25°C (68°F to 77°F).
• Protect from light and moisture.
• Dispense in a tight, light-resistant container with a child-resistant closure.
  

Safety Advice

• Cardiovascular Risk: NSAIDs may increase the risk of serious cardiovascular thrombotic events, including heart attack and stroke.
• Gastrointestinal Risk: NSAIDs can cause serious gastrointestinal adverse events, including bleeding, ulceration, and perforation of the stomach or intestines.
• Contraindications: Not recommended for use in patients with known hypersensitivity to indomethacin or other NSAIDs, or in those who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
• Pregnancy: Use during pregnancy should be avoided, especially in the third trimester.
• Interactions: Inform your doctor about all other medications you are taking to avoid potential interactions.
  

Product Substitutes

• Generic Indomethacin 25 mg Capsules: Available from various manufacturers.
• Alternative NSAIDs: Depending on the condition being treated, alternatives may include ibuprofen, naproxen, diclofenac, or celecoxib.
  

Manufacturer/Marketer

Letap Pharmaceuticals

Country of Origin

• Ghana