Description:

Ivermectin cream  is a topical prescription medication containing 1% ivermectin. It is used to treat inflammatory lesions (bumps and pimples) of rosacea in adults, helping reduce redness, swelling, and papulopustular symptoms on the face. It has anti-inflammatory and antiparasitic effects (targeting Demodex mites associated with rosacea) with once-daily application.

Prescription:

• Yes

Therapeutic Category:

• Topical Antiparasitic / Anti-Inflammatory Agent / Rosacea Treatment

Active Ingredients/Composition:

• Ivermectin 1% w/w (10 mg per gram) in a white to pale yellow hydrophilic cream base.

Variant:

• Standard 1% cream (tubes of 30 g, 45 g, or 60 g with or without a calibrated applicator in some markets). Preservative-free or generic versions may be available in certain regions, but the primary variant is the preserved cream. (Note: A separate 0.5% lotion form exists for head lice, e.g., Sklice, but this is the 1% cream for rosacea.)

Consume Type:

• Topical (dermal – applied to affected facial skin)

Directions/Usage:

• Apply a pea-sized amount to each affected area of the face (forehead, chin, nose, each cheek) once daily, using fingertips to spread as a thin layer across the entire affected area (avoid eyes, mouth, and mucous membranes). Use the lowest effective dose and shortest duration needed. Wash hands after application. Cosmetics or sunscreen can be applied after the cream dries. Follow your doctor’s exact prescription; treatment may continue for up to 4 months or longer if effective, with periodic re-evaluation.

Common Side Effects:

• Skin burning sensation, skin irritation, dry skin, itching, or redness at the application site (usually mild and transient). Less common: eye irritation/redness, conjunctivitis, dandruff-like scaling, or worsening of rosacea symptoms initially. Serious (rare): severe allergic reactions (rash, swelling, difficulty breathing) or systemic effects (unlikely due to low absorption).

Package Type:

• Tube

Storage Advice:

• Store at controlled room temperature 20–25°C (68–77°F); excursions permitted 15–30°C (59–86°F). Protect from light and freezing. Keep tightly closed and out of reach of children. Discard after expiry or if discolored/separated.

Safety Advice:

• Prescription only; use under medical supervision. For external use only—avoid eyes, mouth, mucous membranes, or broken skin. Contraindicated if hypersensitive to ivermectin or any ingredient. Caution in pregnancy (limited data—use only if benefits outweigh risks), breastfeeding (minimal absorption, but consult doctor), or children (safety not established under 18 years). Report severe irritation, persistent worsening, or signs of allergy immediately. Not for oral, ophthalmic, or intravaginal use. May cause transient aggravation of rosacea initially (usually resolves). Use sunscreen and sun protection on treated areas.

Product Substitutes:

• Generic Ivermectin 1% Cream (e.g., Teva, Zydus, or other generics)
• Soolantra (original brand by Galderma)
• Other topical rosacea treatments: Metronidazole cream/gel (e.g., Rozex, Metrogel), Azelaic acid 15% gel (Finacea), Brimonidine gel (Mirvaso for redness), or Sodium sulfacetamide/sulfur preparations
• For severe cases: Oral antibiotics or isotretinoin (under dermatologist guidance)

Manufacturer/Marketer:

• Galderma Laboratories, L.P.

Country of Origin:

• United States