A combination antimalarial therapy (ACT: Artemether + Lumefantrine) in suspension (liquid) form, intended to treat uncomplicated malaria, usually caused by Plasmodium falciparum. Suspension form is often used for children or those who have difficulty swallowing tablets.
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Description:
A combination antimalarial therapy (ACT: Artemether + Lumefantrine) in suspension (liquid) form, intended to treat uncomplicated malaria, usually caused by Plasmodium falciparum. Suspension form is often used for children or those who have difficulty swallowing tablets.
Prescription:
Over the Counter
Therapeutic Category:
Antimalarial agent, specifically Artemisinin‑based Combination Therapy (ACT).
Active Ingredients / Composition:
Artemether + Lumefantrine in fixed combination.
Variant:
Oral suspension (powder for suspension which must be reconstituted).
Different bottle sizes, e.g. 60 mL is common.
Consume Type:
Oral use (by mouth).
Suspension: reconstituted with appropriate diluent (usually water) and shaken well before use.
Directions / Usage:
Dose usually weight‑based, especially in children.
Typical regimen: multiple doses over 3 days. For example: an initial dose, then second dose after 8 hours, then twice daily doses for the next 2 days.
Taken with food (or at least something fatty) to enhance lumefantrine absorption.
Common Side Effects:
Some known side effects of Artemether + Lumefantrine combinations include:
Headache, dizziness
Nausea, vomiting, anorexia (loss of appetite)
Abdominal pain
Rare: changes in heart rhythm (QT interval prolongation) especially with other interacting drugs
Package Type:
Powder for oral suspension, supplied as a bottle (often 60 mL) with dry powder plus instructions for reconstitution.
After reconstitution, it’s used over the course of the treatment days.
Storage Advice:
Store in a cool, dry place, protected from extreme heat.
Once reconstituted, stability may be limited — must follow manufacturer instructions on how long the suspension remains effective after mixing.
Keep out of reach of children.
Safety Advice:
Must complete full course even if symptoms improve early to avoid treatment failure or resistance.
Not recommended in severe malaria (i.e. when complications are present) unless under hospital care.
Be cautious in patients with liver or heart issues, or taking other medications that affect heart rhythm (QT prolongation risk).
Avoid use in infancy / low body weight unless the brand and regulatory authority approve a pediatric formulation.
In pregnancy: may be used after risk‑benefit assessment (Artemether/Lumefantrine is used in pregnancy under certain conditions; local guidelines apply).
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