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Natrixam 1.5 mg/10 mg Tablets

Natrixam 1.5 mg/10 mg Tablets

Natrixam is a fixed-dose combination medication used for the treatment of high blood pressure (essential hypertension). It combines two antihypertensive agents:

  • Indapamide (a thiazide-like diuretic)
  • Amlodipine (a calcium channel blocker)

This combination is prescribed as a substitution therapy for patients already controlled with indapamide and amlodipine taken separately at the same dose levels. 

Price: 10.50 /Tablet

Key Product Information

Antihypertensive

Oral administration.

Indapamide: 1.5 mg Amlodipine Besilate: 13.87 mg (equivalent to 10 mg of amlodipine)​

Blister pack

Manufacturer: Les Laboratoires Servier Industrie Applicant/Marketer: Assene-Laborex Limited

France
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Product description

Description:

Natrixam is a fixed-dose combination medication used for the treatment of high blood pressure (essential hypertension). It combines two antihypertensive agents:

  • Indapamide (a thiazide-like diuretic)
  • Amlodipine (a calcium channel blocker)

This combination is prescribed as a substitution therapy for patients already controlled with indapamide and amlodipine taken separately at the same dose levels. 

Prescription:

  • Prescription-only medicine (POM)

Dosage:

  • One tablet once daily, preferably taken in the morning.
  • Swallow the tablet whole with water; do not chew or crush.
  • Not suitable for initiating therapy; dosage adjustments should be made with individual components if necessary.

Therapeutic Category:

  • Antihypertensive Agent​

Active Ingredients/Composition:

  • Indapamide: 1.5 mg
  • Amlodipine Besilate: 13.87 mg (equivalent to 10 mg of amlodipine)​

Each tablet also contains excipients such as lactose monohydrate.

Variant:

  • Available in a 1.5 mg/10 mg strength.
  • Also available in a 1.5 mg/5 mg strength.

Consume Type:

  • Oral administration (modified-release tablet)

Directions/Usage:

  • Take one tablet daily in the morning.
  • Swallow whole with water; do not chew or crush.
  • Consistent daily intake at the same time is recommended for optimal blood pressure control. ​

Common Side Effects:

  • Dizziness
  • Headache
  • Peripheral edema (swelling of ankles or feet)
  • Fatigue
  • Nausea
  • Flushing

Note: If any side effects persist or worsen, consult your healthcare provider.

Package Type:

  • Blister pack containing 30 modified-release tablets.

Storage Advice:

  • Store below 30°C (86°F).
  • Keep in the original packaging to protect from moisture.
  • Keep out of reach of children.​

Safety Advice:

  • Not recommended for patients with severe renal impairment (creatinine clearance <30 ml/min).
  • Use with caution in patients with liver impairment.
  • Not indicated for use in children and adolescents under 18 years.
  • Consult your doctor if pregnant, planning to become pregnant, or breastfeeding.

Product Substitutes:

  • Natrilam 1.5 mg/10 mg Tablet SR: Contains the same active ingredients and strength.
  • Separate administration of Indapamide 1.5 mg and Amlodipine 10 mg tablets

Note: Always consult your healthcare provider before switching medications.

Manufacturer/Marketer:

  • Manufacturer: Les Laboratoires Servier Industrie
  • Applicant/Marketer: Assene-Laborex Limited

Country of Origin:

  • France 

 

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