Neostigmine Injection 10mg/20ml

Neostigmine Injection 10mg/20ml

Neostigmine is an anticholinesterase agent used to reverse the effects of non-depolarizing neuromuscular blocking agents after surgery and to treat conditions like myasthenia gravis and postoperative urinary retention. It increases the levels of acetylcholine at neuromuscular junctions by inhibiting acetylcholinesterase.

Price: ₵120.00

Key Product Information

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Category: Prescription Only Medicine (PoM)

Product description

Description:

Prescription:

Yes, Neostigmine is a prescription-only medication.

Therapeutic Category:

Cholinesterase Inhibitor
Reversal Agent (Neuromuscular Blockade Reversal)
Parasympathomimetic Agent

Active Ingredients/Composition:

Neostigmine Methylsulfate 10 mg/20 mL
(Concentration: 0.5 mg/mL)

Vitamins:

None

Minerals:

None

Variant:

Typically available as:
- 10 mg/20 mL multi-dose vial
- Also available in ampoules (e.g., 0.5 mg/mL in 1 mL or 5 mL ampoules)

Consume Type:

Parenteral (Intramuscular, Intravenous, or Subcutaneous injection)
Administered only by healthcare professionals

Directions/Usage:

Reversal of neuromuscular blockade: Given IV, typically alongside an anticholinergic (e.g., atropine or glycopyrrolate) to counteract muscarinic side effects.
Myasthenia gravis: Dosage individualized, can be given IM or SC.
Dose and administration route depend on clinical condition and patient response.
Must be administered under close medical supervision.

Common Side Effects:

Nausea and vomiting
Abdominal cramps
Bradycardia
Increased salivation
Bronchial secretions
Muscle cramps
Sweating
Rare: Heart block, hypotension, or allergic reactions

Package Type:

Glass vials or ampoules
Commonly in multi-dose vials (20 mL)
Packed in boxes with a package insert

Storage Advice:

Store at 15°C to 25°C (59°F to 77°F)
Protect from light
Do not freeze
Use within specified period after opening (refer to label)

Safety Advice:

Use with caution in patients with:
- Asthma, bradycardia, or recent coronary occlusion
- Peptic ulcer or peritonitis
Contraindicated in mechanical intestinal or urinary obstruction
Anticholinergic (e.g., atropine) often co-administered to prevent muscarinic effects
Monitor heart rate, respiratory function, and muscarinic side effects during use
Use during pregnancy only if clearly needed