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Phenobarbitone Injection

Phenobarbitone Injection

Phenobarbitone (also known as Phenobarbital) is a long-acting barbiturate primarily used as an anticonvulsant. It is commonly administered to manage seizures, including generalized and partial seizures, and is also used for sedation in certain medical conditions.

Price: 60.00

Key Product Information

Anticonvulsant Sedative-Hypnotic

Injectable (administered intravenously (IV) or intramuscularly (IM)). Not for oral consumption.

Phenobarbitone (active ingredient): 30–200 mg per ampoule 

Vial

Abbott Laboratories

UK
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Product description

 Description:

Phenobarbitone (also known as Phenobarbital) is a long-acting barbiturate primarily used as an anticonvulsant. It is commonly administered to manage seizures, including generalized and partial seizures, and is also used for sedation in certain medical conditions.

Prescription:

  • Prescription-only medication (POM) 

Dosage:

  • Adults: Typical dosage varies based on condition. For seizures, an initial dose of 100–200 mg IM/IV, followed by maintenance doses as advised by the physician.
  • Children: Dosage is weight-based and usually ranges between 1–3 mg/kg/day.
  • Dosage should always be individualized based on the patient’s condition and response.

Therapeutic Category:

  • Anticonvulsant
  • Sedative-Hypnotic

Active Ingredients/Composition:

  • Phenobarbitone (active ingredient): 30–200 mg per ampoule 

Variant:

  • Available in varying strengths such as 30 mg/mL, 60 mg/mL, or 120 mg/mL ampoules.

Consume Type:

  • Injectable (administered intravenously (IV) or intramuscularly (IM)). Not for oral consumption.

Directions/Usage:

  1. Administer only under the supervision of a healthcare provider.
  2. Follow aseptic techniques for IM/IV administration.
  3. Dilute appropriately if given intravenously, and administer slowly to prevent respiratory depression or hypotension.
  4. Monitor vital signs during administration.

Common Side Effects:

  • Drowsiness
  • Dizziness or lightheadedness
  • Respiratory depression (at high doses or rapid IV administration)
  • Nausea or vomiting
  • Hypotension
  • Allergic reactions (rash, swelling, or anaphylaxis in rare cases)

Package Type:

  • Supplied in glass ampoules or vials. Typically available in packs of 5 or 10 ampoules.

Storage Advice:

  • Store in a cool, dry place below 25°C (77°F).
  • Keep away from direct sunlight and moisture.
  • Do not freeze.

Safety Advice:

  • Pregnancy & Breastfeeding: Use with caution. Phenobarbitone may cross the placenta and is excreted in breast milk.
  • Alcohol: Avoid alcohol during treatment as it may increase sedation.
  • Driving/Operating Machinery: Avoid activities requiring alertness due to drowsiness or impaired motor coordination.
  • Renal/Hepatic Impairment: Use cautiously; dosage adjustment may be needed.
  • Risk of dependence or withdrawal symptoms with prolonged use.

Product Substitutes:

  • Phenobarb Injection
  • Luminal Sodium Injection
  • Gardenal Injection

(Note: Substitutes vary by region and manufacturer. Always consult your pharmacist or doctor.)

Manufacturer/Marketer:

  • Abbott Laboratories

Country of Origin:

  • UK

Additional information

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