Description:
Phenobarbitone (also known as Phenobarbital) is a long-acting barbiturate primarily used as an anticonvulsant. It is commonly administered to manage seizures, including generalized and partial seizures, and is also used for sedation in certain medical conditions.
Prescription:
- Prescription-only medication (POM)
Dosage:
- Adults: Typical dosage varies based on condition. For seizures, an initial dose of 100–200 mg IM/IV, followed by maintenance doses as advised by the physician.
- Children: Dosage is weight-based and usually ranges between 1–3 mg/kg/day.
- Dosage should always be individualized based on the patient’s condition and response.
Therapeutic Category:
- Anticonvulsant
- Sedative-Hypnotic
Active Ingredients/Composition:
- Phenobarbitone (active ingredient): 30–200 mg per ampoule
Variant:
- Available in varying strengths such as 30 mg/mL, 60 mg/mL, or 120 mg/mL ampoules.
Consume Type:
- Injectable (administered intravenously (IV) or intramuscularly (IM)). Not for oral consumption.
Directions/Usage:
- Administer only under the supervision of a healthcare provider.
- Follow aseptic techniques for IM/IV administration.
- Dilute appropriately if given intravenously, and administer slowly to prevent respiratory depression or hypotension.
- Monitor vital signs during administration.
Common Side Effects:
- Drowsiness
- Dizziness or lightheadedness
- Respiratory depression (at high doses or rapid IV administration)
- Nausea or vomiting
- Hypotension
- Allergic reactions (rash, swelling, or anaphylaxis in rare cases)
Package Type:
- Supplied in glass ampoules or vials. Typically available in packs of 5 or 10 ampoules.
Storage Advice:
- Store in a cool, dry place below 25°C (77°F).
- Keep away from direct sunlight and moisture.
- Do not freeze.
Safety Advice:
- Pregnancy & Breastfeeding: Use with caution. Phenobarbitone may cross the placenta and is excreted in breast milk.
- Alcohol: Avoid alcohol during treatment as it may increase sedation.
- Driving/Operating Machinery: Avoid activities requiring alertness due to drowsiness or impaired motor coordination.
- Renal/Hepatic Impairment: Use cautiously; dosage adjustment may be needed.
- Risk of dependence or withdrawal symptoms with prolonged use.
Product Substitutes:
- Phenobarb Injection
- Luminal Sodium Injection
- Gardenal Injection
(Note: Substitutes vary by region and manufacturer. Always consult your pharmacist or doctor.)
Manufacturer/Marketer:
Country of Origin:
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