Thiamine (Vitamin B1) injection is a water‑soluble vitamin preparation used to prevent or treat thiamine deficiency. It’s used when rapid restoration of vitamin B1 levels is needed, especially in conditions like beriberi, Wernicke’s encephalopathy, severe vomiting (e.g. in pregnancy), or when oral absorption is compromised.
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Description:
Thiamine (Vitamin B1) injection is a water‑soluble vitamin preparation used to prevent or treat thiamine deficiency. It’s used when rapid restoration of vitamin B1 levels is needed, especially in conditions like beriberi, Wernicke’s encephalopathy, severe vomiting (e.g. in pregnancy), or when oral absorption is compromised.
Prescription:
Prescription‐only for injectable
Therapeutic Category:
Vitamin supplement / Vitamin B complex class
Nutrient / Metabolism therapy
Active Ingredients / Composition:
Active ingredient: Thiamine hydrochloride (Vitamin B1) in injectable solution. Typical concentration is 100 mg/mL in many formulations.
Variant:
Dosages / strengths vary (commonly 100 mg/mL; also lower strengths like 50 mg/mL depending on product)
Injection route: Intramuscular (IM) or Intravenous (IV) (slow injection or infusion)
Formulated as sterile solution for parenteral administration.
Consume Type:
Parenteral: by injection — either IM (intramuscular) or IV (intravenous) route.
Directions / Usage:
Dosing depends on cause / severity of deficiency. Examples: for adult beriberi, 10‑20 mg IM three times daily for up to 2 weeks; for Wernicke’s encephalopathy, initial IV dose 100 mg followed by daily doses until improvement.
In patients with marginal thiamine status being given IV dextrose, prophylactic thiamine may be given to avoid precipitating complications.
Frequency and duration depend on patient condition (diet, absorption, severity) and response.
Common Side Effects:
Some known / possible adverse effects include:
Feeling of warmth, flushing
Pruritus (itching), urticaria (hives)
Sweating, restlessness
Nausea, possibly tightness in the throat
Tenderness or induration at site of IM injection
Rare allergic or hypersensitivity reactions, including swelling, anaphylaxis in extreme cases.
Package Type:
Ampoules or vials of sterile solution. Commonly small volume (1 mL or 2 mL) ampoules for 50 mg or 100 mg doses.
Often packaged single‑dose ampoules; may come in multi‑pack boxes.
Storage Advice:
Store at room temperature, protected from extreme heat. Some directions say below ~25‑30 °C.
Protect from light.
Keep sterile, check for particulates/discoloration before use.
Use only unexpired product; once opened or prepared per instructions.
Safety Advice:
Do not use if allergic to thiamine or any component of the injection.
Use with caution in patients with kidney disease.
Monitor for hypersensitivity reactions during or after injection.
In emergency use (e.g. Wernicke’s), ensure supportive care.
Oral nutrition and dietary correction often needed alongside injection.
Product Substitutes:
Other brands / generics of thiamine hydrochloride injection.
Other forms of vitamin B1 (oral tablets, etc.) when injections are not required or possible.
In some cases, combination vitamin B‑complex preparations may be used when multiple deficiencies are suspected.
Manufacturer / Marketer:
Country of Origin:
USA
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