Description:

Time Herbal Mixture is a traditional Ghanaian herbal remedy (liquid mixture) primarily used for the management and treatment of malaria symptoms, including fever, loss of appetite, and general malaise associated with uncomplicated malaria. It is a popular over-the-counter herbal product in Ghana and parts of West Africa, formulated from local medicinal plants with reported antimalarial properties. Studies have evaluated its clinical safety and effectiveness as an adjunct or alternative in mild cases, with a generally good safety profile when used as directed.

Prescription:

• No

Therapeutic Category:

• Herbal Antimalarial / Traditional Medicine / Antipyretic and Appetizer Stimulant (used for malaria symptom relief and immune support in traditional contexts)

Active Ingredients/Composition:

• Aqueous extract blend primarily from: Cola gigantea (leaves or bark), Solanum torvum (leaves/fruits), Spathodea campanulata (leaves/bark), Bombax buonopozense (leaves/bark), and Vernonia amygdalina (bitter leaf). These plants contain bioactive compounds like alkaloids, flavonoids, terpenoids, and saponins traditionally associated with antimalarial, anti-inflammatory, and antipyretic effects. Exact concentrations and preparation ratios are proprietary to the manufacturer.

Variant:

• Standard liquid mixture (bitter-tasting herbal decoction); commonly available in 500 ml bottles (most common retail size); no major flavored or concentrated sub-variants noted, though some sellers offer smaller trial sizes

Consume Type:

• Oral

Directions/Usage:

• Shake well before use. Adults: Typically 30 ml (about 2 tablespoons) three times daily (morning, afternoon, evening) before or after meals, or as directed by a herbalist/pharmacist. Children: Dose reduced based on age/weight (e.g., 15–20 ml twice daily for older children; consult professional). Often taken for 5–7 days or until symptoms improve. Best combined with adequate hydration and rest. Not a substitute for confirmed malaria diagnosis or artemisinin-based combination therapies (ACTs) recommended by Ghana Health Service guidelines.

Common Side Effects:

• Generally well-tolerated in short-term use; mild and rare effects may include stomach upset, nausea, bitter aftertaste, mild diarrhea, or temporary loss of appetite (due to bitterness). Studies report no significant adverse effects in participants, with normal liver, kidney, and blood profiles post-use. Rare: allergic reactions (rash, itching) or gastrointestinal discomfort in sensitive individuals.

Package Type:

• Plastic bottle of 500 ml

Storage Advice:

• Store in a cool, dry place at room temperature (below 25–30°C), away from direct sunlight and heat. Keep tightly closed after opening. Refrigerate if possible after opening to maintain potency (though not always required). Keep out of reach of children. Use within expiry date (typically 1–2 years unopened; check label).

Safety Advice:

• Not a replacement for standard antimalarial drugs (e.g., ACTs like artemether-lumefantrine) in confirmed malaria cases—seek rapid diagnostic testing and professional medical care, especially for severe symptoms (high fever, convulsions, vomiting). Consult a doctor/herbalist before use in pregnancy, breastfeeding, children under 12, or those with liver/kidney issues. Avoid if allergic to any plant ingredients. Do not exceed recommended dose to prevent GI irritation. If symptoms persist >3 days, worsen, or include severe signs (e.g., jaundice, confusion), seek immediate medical help. Herbal products may interact with medications or vary in potency—use from reputable sources.

Product Substitutes:

• Taabea Herbal Mixture (similar antimalarial herbal blend with Azadirachta indica, etc.)
• Masada Mixture or Cryptolepis sanguinolenta-based products (Ghanaian quinine)
• Other local antimalarial herbals like Givers Herbal Mixture or Tinattet Malakare
• Standard pharmaceutical antimalarials (e.g., Coartem, Lonart) for confirmed malaria
• Vernonia amygdalina (bitter leaf) decoctions or other traditional mixes

Manufacturer/Marketer:

• Kenoga Company Limited

Country of Origin:

• Ghana