Description:

Uperio 200mg Tablet contains febuxostat, a xanthine oxidase inhibitor used to treat chronic hyperuricemia (high uric acid levels) in adults with gout where urate deposition has occurred (e.g., gouty arthritis or tophi). It lowers uric acid production to prevent gout flares but is not for acute attacks.

Prescription:

• Prescription required; consult a physician before use.

Therapeutic Category:

• Anti-gout / Xanthine oxidase inhibitor (for hyperuricemia management).

Active Ingredients/Composition:

• Febuxostat IP 200 mg per tablet.

Variant:

• 200 mg tablets (higher strength; common variants include 40 mg, 80 mg, 120 mg).

Consume Type:

• Oral (tablet form).

Directions/Usage:

• Take 1 tablet once daily, with or without food. Swallow whole with water. For patients with renal impairment (eGFR <30 mL/min), start at lower dose (e.g., 40-80 mg) and titrate. Continue long-term; may take weeks to months for full effect. Use colchicine/NSAIDs for flare prophylaxis initially.

Common Side Effects:

• Nausea, diarrhea, headache, arthralgia (joint pain), rash, abnormal liver function tests, edema. Serious: Increased cardiovascular death risk (heart attack, stroke), severe skin reactions, gout flares (initially), liver injury.

Package Type:

• Strip pack of 28 tablets.

Storage Advice:

• Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Safety Advice:

• Monitor liver enzymes, uric acid, and CV risk regularly (higher mortality vs. allopurinol in trials). Not for acute gout attacks or asymptomatic hyperuricemia. Caution in heart disease, renal/hepatic impairment, pregnancy (Category C), breastfeeding. Avoid alcohol; inform doctor of theophylline use (interaction). Black box warning: CV death risk.

Product Substitutes:

• Febustat, Feburic, Zurig, Febuday, Uloric (febuxostat brands); Allopurinol (alternative). Consult a doctor.

Manufacturer/Marketer:

• Ipca Laboratories Ltd

Country of Origin:

• India.