Description:

Vecuronium is a non-depolarizing skeletal muscle relaxant used as an adjunct to general anesthesia to facilitate tracheal intubation and provide skeletal muscle relaxation during surgery or mechanical ventilation. It acts by blocking acetylcholine at the neuromuscular junction.

Prescription:

• Yes, it is a prescription-only medication, typically used in hospitals or surgical settings.

Therapeutic Category:

• Neuromuscular Blocking Agent (Non-depolarizing Type)
  
• Muscle Relaxant (Anesthesia adjunct)

Active Ingredients/Composition:

• Vecuronium Bromide 100 mg (as lyophilized powder for injection)
  

Vitamins:

• None

Minerals:

• None
  

Variant:

• Lyophilized powder for intravenous injection

• Available in different vial strengths (commonly 4 mg, 10 mg, 20 mg, and 100 mg vials)

Consume Type:

• Parenteral (Intravenous injection only)

• Administered only by trained medical professionals

Directions/Usage:

• Reconstitute the 100 mg vial with a suitable diluent (commonly sterile water or saline).

• Administer intravenously as a bolus injection or continuous infusion.

• Dosage depends on patient weight, anesthetic technique, and duration of procedure.

• Used under strict monitoring of neuromuscular function.

Common Side Effects:

• Respiratory depression or paralysis (if not properly ventilated)

• Hypotension

• Bradycardia

• Prolonged paralysis

• Rare: Anaphylaxis, skin reactions

Package Type:

• Glass vial containing 100 mg lyophilized powder

• May be packaged singly or in packs with instruction leaflet

Storage Advice:

• Store below 25°C (77°F)

• Protect from light and moisture

• Use immediately after reconstitution or as per label instructions

• Do not freeze reconstituted solution

Safety Advice:

• Administer only in facilities with airway and ventilatory support available

• Continuous monitoring of respiratory and neuromuscular function is essential

• Contraindicated in patients with hypersensitivity to vecuronium or bromides

• Caution in patients with myasthenia gravis or other neuromuscular diseases

• Use with care in patients with hepatic or renal impairment
  

Product Substitutes:

• Pancuronium Bromide

• Rocuronium Bromide

• Atracurium Besylate

• Cisatracurium
  (Selection depends on clinical context and anesthesiologist’s preference)

Manufacturer/Marketer:

• Vecuronium is available under multiple brand names from various manufacturers globally.
  Examples include:
  • Organon (subsidiary of Merck) – Original brand

  • Neon Laboratories, Cipla, Fresenius Kabi, Pfizer, and other generic pharmaceutical companies.
    

Country of Origin:

• Varies by brand.
  • Original brand: Netherlands/USA (Organon/Merck)

  • Generics: India, Germany, USA, etc.