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Acetylcysteine Injection

Acetylcysteine Injection

Acetylcysteine Injection is a sterile solution used to treat acetaminophen overdose by replenishing glutathione stores, thereby detoxifying harmful metabolites. It is also employed as a mucolytic agent to reduce the viscosity of pulmonary secretions. ​

Price: 170.00

Key Product Information

Pharmacological Class: Antidote; Mucolytic Agent​

Administered intravenously (IV) after appropriate dilution.​

Active Ingredient: Acetylcysteine 200 mg/mL Inactive Ingredients: Edetate Disodium, Sodium Hydroxide (for pH adjustment), Water for Injection

Supplied in 30 mL single-dose glass vials.

Manufactured by various pharmaceutical companies, including: Almaject, Inc. Fresenius Kabi Akorn Operating Company LLC ​

Manufactured in multiple countries, including the United States and India, depending on the manufacturer.​
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Product description

Description

Acetylcysteine Injection is a sterile solution used to treat acetaminophen overdose by replenishing glutathione stores, thereby detoxifying harmful metabolites. It is also employed as a mucolytic agent to reduce the viscosity of pulmonary secretions. ​

Prescription

This medication is prescription-only and should be administered under medical supervision.​

Therapeutic Category

  • Pharmacological Class: Antidote; Mucolytic Agent​

Active Ingredients/Composition

  • Active Ingredient: Acetylcysteine 200 mg/mL 
  • Inactive Ingredients: Edetate Disodium, Sodium Hydroxide (for pH adjustment), Water for Injection

Vitamins

None.​

Minerals

None.​

Variant

Available as a 20% solution (200 mg/mL) in 30 mL single-dose vials containing 6 g of acetylcysteine. ​

Consume Type

Administered intravenously (IV) after appropriate dilution.​

Directions/Usage

  • Indication: Treatment of acetaminophen overdose. 
  • Administration: Must be diluted prior to IV infusion. 
  • Dosage: Follows a specific protocol involving loading and maintenance doses over a 21-hour period. 
  • Note: The solution may change color upon exposure to air; this does not affect its efficacy. 

Common Side Effects

  • Nausea and vomiting 
  • Flushing 
  • Hypersensitivity reactions (e.g., rash, pruritus) 
  • Hypotension 
  • Bronchospasm ​

Package Type

Supplied in 30 mL single-dose glass vials.

Storage Advice

  • Temperature: Store at 20° to 25°C (68° to 77°F). 
  • Handling: Do not use previously opened vials for IV administration. 
  • Shelf Life: 24 months unopened; once diluted, use within 3 hours. 

Safety Advice

  • Monitor for signs of hypersensitivity during administration. 
  • Use with caution in asthmatic patients due to potential bronchospasm. 
  • Ensure proper dilution and administration protocols are followed.​

Product Substitutes

Equivalent products include:

  • Acetadote® (Cumberland Pharmaceuticals) 
  • Generic versions by various manufacturers​

Manufacturer/Marketer

Manufactured by various pharmaceutical companies, including:

  • Almaject, Inc. 
  • Fresenius Kabi 
  • Akorn Operating Company LLC ​

Country of Origin

Manufactured in multiple countries, including the United States and India, depending on the manufacturer.​

 

Additional information

Additional information

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