Description:

Uperio 50mg Tablet contains febuxostat, a xanthine oxidase inhibitor used to treat chronic hyperuricemia in adults with gout where urate deposition has occurred (e.g., tophi, gouty arthritis). It reduces uric acid production to prevent gout attacks but is not for acute gout flares.

Prescription:

• Prescription required; consult a physician before use.

Therapeutic Category:

• Anti-gout / Xanthine oxidase inhibitor (for hyperuricemia in gout).

Active Ingredients/Composition:

• Febuxostat 50 mg per tablet; inactive ingredients may include lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, and film-coating agents.

Variant:

• Available in 50 mg, 100 mg, and 200 mg tablet strengths.

Consume Type:

• Oral (tablet form).

Directions/Usage:

• Take 1 tablet once daily, with or without food. Swallow whole with water. Usual starting dose is 40–80 mg; 50 mg may be used in mild cases or renal impairment. Increase to 80–100 mg if uric acid >6 mg/dL after 2–4 weeks. Use with colchicine or NSAID for first 3–6 months to prevent flares. Long-term treatment; monitor serum uric acid.

Common Side Effects:

• Gout flares (initially), nausea, diarrhea, headache, joint pain, rash, abnormal liver function, swelling. Serious: Cardiovascular death (higher risk in heart disease), severe skin reactions, liver damage.

Package Type:

• Strip or blister pack of 28 or 30 tablets.

Storage Advice:

• Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Safety Advice:

• Black box warning: Increased risk of cardiovascular death in patients with heart disease—use only if allopurinol is inadequate. Not for acute gout or asymptomatic high uric acid. Monitor liver function, uric acid, and CV risk. Avoid in severe liver/kidney disease, pregnancy (Category C), or breastfeeding. Avoid alcohol. Do not use with azathioprine, mercaptopurine, or theophylline (serious interactions). Not for children.

Product Substitutes:

• Feburic, Febustat, Zurig, Uloric (febuxostat); Allopurinol (first-line). Consult a doctor.

Manufacturer/Marketer:

• Scab Pharmacy Limited (marketer in Ghana); generic formulation.

Country of Origin:

• India.