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Vegatem [Artemether+Lumefantrine] 80/480mg Tablet

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Vegatem [Artemether+Lumefantrine] 80/480mg Tablet

A fixed‑dose antimalarial tablet combining Artemether 80 mg and Lumefantrine 480 mg. Used for treating uncomplicated Plasmodium falciparum malaria. The combination provides fast parasite killing (artemether) and eradicates residual parasites (lumefantrine).

Price: 43.00

Key Product Information

Artemisinin‑based Combination Therapy (ACT). Antimalarial agent.

Oral (tablet).

Artemether 80 mg per tablet. Lumefantrine 480 mg per tablet.

Blister pack

Vega Pharmaceuticals

UK
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Product description

 Description:
A fixed‑dose antimalarial tablet combining Artemether 80 mg and Lumefantrine 480 mg. Used for treating uncomplicated Plasmodium falciparum malaria. The combination provides fast parasite killing (artemether) and eradicates residual parasites (lumefantrine).

Prescription:

  • Over‑the‑counter (OTC)

Therapeutic Category:

  • Artemisinin‑based Combination Therapy (ACT).

  • Antimalarial agent.

Active Ingredients / Composition:

  • Artemether 80 mg per tablet.

  • Lumefantrine 480 mg per tablet.

Variant:

  • The 80/480 mg tablet is one of the higher strength variants of Artemether + Lumefantrine.

  • Other variants include lower dose forms for pediatric use (e.g. 20/120 mg tablets, dispersible forms).

Consume Type:

  • Oral administration (by mouth).

Directions / Usage:

  • Treatment schedule commonly spans 3 days, with several doses. For example:
     • First dose at time zero,
     • Second dose ~8 hours later,
     • Then twice daily (morning and evening) for the next two days.

  • Must be taken with food (preferably something containing fat or milk) to improve lumefantrine absorption.

  • Complete full course, even if symptoms resolve before finishing tablets.

Common Side Effects:
Some of the regularly reported side effects include:

  • Headache

  • Dizziness

  • Loss of appetite (anorexia)

  • Nausea, sometimes vomiting

  • Abdominal pain or discomfort

  • Possible transient increases in liver enzymes

  • Rare: changes in heart rhythm (QT interval prolongation) especially in patients with risk factors or taking other interacting drugs

Package Type:

  • Blister packs

Storage Advice:

  • Store at room temperature, away from extreme heat or cold.

  • Keep in a dry place. Protect from moisture and direct sunlight.

  • Keep out of reach of children.

Safety Advice:

  • Use only for confirmed or strongly suspected malaria; seek medical diagnosis.

  • Complete full course to prevent resistance and relapse.

  • Avoid in patients with known hypersensitivity to artemether, lumefantrine, or any excipient.

  • Use caution (or avoid) in patients with heart problems, especially those predisposed to QT prolongation.

  • Not generally recommended for severe malaria or where intravenous therapy is required.

  • Pregnancy and breastfeeding: use only if benefits outweigh risks and under medical supervision – local guidelines vary.

Product Substitutes:

  • Other tablets or fixed combinations of Artemether + Lumefantrine (brand or generic), such as Coartem, Lonart, etc.

  • Lower strength or dispersible versions where appropriate for children.

  • Other antimalarial ACT regimens (depending on local malaria drug resistance and treatment guidelines).

 Manufacturer / Marketer:

  • Vega

 Country of Origin:

  • UK

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Additional information

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