Description: 

• An advanced, one-a-day oral tablet that combines three distinct blood pressure medications into a single pill to improve heart protection and simplify treatment. 

Prescription: 

• Strictly Prescription-Only (Rx). 

Therapeutic Category: 

• Antihypertensive agent (Combination of a Calcium Channel Blocker, an Angiotensin II Receptor Blocker, and a Thiazide Diuretic). 

• Active Ingredients/Composition: Each single film-coated tablet supplies three powerful drugs:
  • Amlodipine (10 mg, as amlodipine besylate): Relaxes and widens your blood vessels so blood flows more smoothly.
  • Valsartan (160 mg): Blocks a natural hormone that tightens blood vessels, keeping them open and relaxed.
  • Hydrochlorothiazide / HCTZ (12.5 mg): A water pill (diuretic) that helps your kidneys flush out extra salt and excess fluid through urine. 

Usage & Forms

Variant: 

• 10mg/160mg/12.5mg film-coated tablets. (The tablets are pale yellow, oval, and marked with “NVR” on one side and “VDL” on the reverse). Other strengths include 5mg/160mg/12.5mg and 10mg/160mg/25mg. 

Consume Type: 

• Oral use only (swallowed whole with water). 
• Directions/Usage:
  • Take exactly 1 tablet once a day, preferably in the morning at the same time each day.
  • Can be taken with or without food.
  • Swallow the tablet whole. Do not crush, split, or chew it. 

Safety & Storage

Common Side Effects: 

• Dizziness, peripheral edema (fluid swelling in the ankles and lower legs), headache, fatigue, mild nausea, and muscle spasms. 

Package Type: 

• Blister strips containing 28 tablets or 30 tablets packed inside a branded cardboard box. 

Storage Advice: 

• Store below 25°C to 30°C in a dry place. Keep the tablets inside their original cardboard box to protect them from ambient light and moisture, away from children. 
• Safety Advice:
  • Black Box Warning / Severe Risk: Never take this medication if you are pregnant or planning to become pregnant. It can cause severe injury, defects, or death to an unborn baby.
  • Do not use this drug if you have severe kidney failure, anuria (inability to produce urine), or severe liver cirrhosis.
  • Do not take potassium supplements or use potassium-based salt substitutes without checking with your doctor, as valsartan can cause blood potassium levels to spike.
  • Avoid drinking grapefruit juice while on this medicine, as it can dangerously alter how amlodipine works.
  • Stand up slowly from sitting positions to prevent postural hypotension (sudden dizziness or fainting). 

Manufacturer/Marketer:

•  Manufactured and marketed globally by the leading Swiss pharmaceutical company Novartis Pharmaceuticals Corporation.

Country of Origin: 

• Switzerland (with regional packaging and printing finalized across various European and global manufacturing hubs). [, 2]